Evidence map›Paper›PMID 41220370›Full record

SynthesisInternational health2026

Pneumonia in Ghana: prevalence, mortality and antimicrobial resistance-a systematic review and meta-analysis.

Frederick Kungu, Aaron Awere-Duodu, Eric S Donkor

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frederick KunguDepartment of Medical Microbiology, University of Ghana Medical School, P.O. Box KB 4236, Accra, Ghana.ORCID 0009-0009-6402-5681
Aaron Awere-DuoduDepartment of Medical Microbiology, University of Ghana Medical School, P.O. Box KB 4236, Accra, Ghana.
Eric S DonkorDepartment of Medical Microbiology, University of Ghana Medical School, P.O. Box KB 4236, Accra, Ghana.

Funding

Research and Capacity Building in Antimicrobial Resistance in West AfricaD43TW012487 · FIC · UNIVERSITY OF GHANA · PI Eric Sampane-Donkor · 2023 to 2026
$986k
Department of Medical MicrobiologyFIC NIH HHS D43 TW012487Fogarty International Center of the National Institutes of HealthNIH HHSResearch and Capacity Building in Antimicrobial Resistance in West AfricaUniversity of Ghana Medical School D43TW012487
6 · The paper itself

Abstract

Pneumonia is a major cause of morbidity and mortality in Ghana, especially among children <5 y of age and the elderly. However, comprehensive data on its prevalence and distribution remain limited. This systematic review addresses this gap by analysing the prevalence, regional variations, risk factors, antimicrobial resistance and mortality rates of pneumonia in Ghana. We searched PubMed, ScienceDirect, Web of Science and African Journals Online databases, including 21 studies with a total of 124 582 participants. A random-effects meta-analysis estimated pooled prevalence and subgroup differences based on age, region and participant type. Heterogeneity was assessed using the I2 test and meta-regression, with sensitivity analysis also conducted. Study quality was evaluated using standardized Joana Briggs Institute checklists for prevalence studies. The pooled prevalence of pneumonia in Ghana was 22.01%, with significant regional variations. The highest prevalence was observed in a study conducted in the Greater Accra and Northern regions (32.31%), while the lowest was in the Upper West (4.83%). The prevalence in children <5 y of age was 17.79%. Hospitalized patients had a higher prevalence (22.14%) than community children (21.49%). Streptococcus pneumoniae was the most common pathogen, with high resistance (>70%) to co-trimoxazole, gentamicin and tetracycline. Key risk factors included indoor air pollution and seasonal changes. The mortality rate for pneumonia was found to be 3.07%. This systematic review highlighted significant regional disparities, pathogen resistance patterns and environmental risk factors that shape the burden of pneumonia in Ghana, providing critical evidence for targeted public health strategies. The findings highlight avenues for future research, including environmental drivers of transmission, focusing on underreported regions and surveillance of antibiotic resistance of pathogens isolated from pneumonia patients.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialPneumoniaChildChild, PreschoolGhanaHumansInfantPrevalenceRisk FactorsStreptococcus pneumoniaeAnti-Bacterial Agentsantimicrobial resistanceC. pneumoniaeGhanapneumoniapneumonia epidemiologyprevalencerespiratory infectionsS. pneumoniaesystematic review

Identifiers

PMID41220370
PMCPMC13154821

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.