Evidence map›Paper›PMID 41220201›Full record

ArticleBrain and behavior2025

The Association Between Stress Hyperglycemia Ratio and Short-Term Outcomes After Successful Recanalization by Mechanical Thrombectomy in Acute Ischemic Stroke Patients.

Xiaobo Li, Chao Jiang, Danni Chen, Wenyong Gao, Xianmin Wang

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xiaobo LiDepartment of Neurology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.
Chao JiangDepartment of Neurology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.
Danni ChenDepartment of Neurology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.
Wenyong GaoDepartment of Neurosurgery, Northern Jiangsu Peopleer Hospital Affiliated to Yangzhou University, Yangzhou, China.
Xianmin WangDepartment of Neurophysiology, Northern Jiangsu Peopleer Hospital Affiliated to Yangzhou University, Yangzhou, China.

Funding

Jiangsu Province 333 Project Scientific Research Project Funding BRA2017168Jiangsu Provincial Department of Human Resources and Social Security Project Funding 2016-WSN-274National Natural Science Foundation of China 81371377
6 · The paper itself

Abstract

objectiveTransient hyperglycemia, known as stress-induced hyperglycemia, often occurs after acute ischemic events. This study aims to examine the relationship between stress hyperglycemia (SHG) and short-term outcomes following successful recanalization by mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS), providing evidence for predicting short-term prognosis.

methodsThis study included AIS patients who underwent MT and achieved successful recanalization between July 2018 and October 2023 at Northern Jiangsu People's Hospital. Stress hyperglycemia ratio (SHR) was calculated using fasting blood glucose (FBG) and glycated hemoglobin (HbA1c) levels at admission to measure SHG. The primary outcome was a poor prognosis at 90 days. Secondary outcomes included early neurological deterioration (END), hemorrhagic transformation (HT), symptomatic intracranial hemorrhage (sICH), and 90-day death. Multivariable logistic regression analysis was performed to evaluate the association between SHR and short-term prognosis.

resultsA total of 394 patients were enrolled. The poor prognosis group had significantly higher SHR than the favorable prognosis group [1.00 (0.87, 1.22) versus 0.82 (0.70, 0.99); p < 0.001]. Multivariable logistic regression analysis confirmed that SHR was independently associated with poor prognosis at 90 days (p < 0.05).

conclusionSHR is associated with both the severity of the condition at admission and a 90-day poor prognosis in AIS patients after successful recanalization by mechanical thrombectomy.

Indexed as

HyperglycemiaIschemic StrokeThrombectomyAgedAged, 80 and overBlood GlucoseBrain IschemiaFemaleGlycated HemoglobinHumansMaleMiddle AgedPrognosisStress, PhysiologicalTreatment OutcomeBlood GlucoseGlycated Hemoglobinacute ischemic strokemechanical thrombectomyprognosisstress hyperglycemia ratiovascular recanalization

Identifiers

PMID41220201
PMCPMC12606005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.