Evidence map›Paper›PMID 41220122›Full record

ArticleJournal of the American Heart Association2025

Differential Performance of Polygenic Score for Coronary Artery Disease Based on Coronary Artery Calcium Between Men Living With and Without HIV.

Genevieve Wojcik, Marios Arvanitis, Sabina Haberlen, Eun-Young Kim, Heejin Kim, Kireem Nam, Matthew J Feinstein, Steven Wolinsky, Joseph B Margolick, Matthew Budoff and 3 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Genevieve WojcikDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0001-7206-8088
Marios ArvanitisDivision of Cardiology, Department of Medicine Johns Hopkins University School of Medicine Baltimore MD USA.
Sabina HaberlenDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-9467-3454
Eun-Young KimDivisions of Infectious Diseases, Department of Medicine Northwestern University Chicago IL USA.
Heejin KimDivisions of Infectious Diseases, Department of Medicine Northwestern University Chicago IL USA.
Kireem NamDivisions of Infectious Diseases, Department of Medicine Northwestern University Chicago IL USA.
Matthew J FeinsteinDivision of Cardiology, Department of Medicine Northwestern University Chicago IL USA.ORCID 0000-0002-8958-7666
Steven WolinskyDivisions of Infectious Diseases, Department of Medicine Northwestern University Chicago IL USA.
Joseph B MargolickDepartment of Molecular Microbiology and Immunology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-4398-8851
Matthew BudoffThe Lundquist Institute at Harbor-UCLA Medical Center Torrance CA USA.ORCID 0000-0002-9616-1946
Jared W MagnaniDivision of Cardiology, Department of Medicine University of Pittsburgh Pittsburgh PA USA.ORCID 0000-0002-5075-3604
Priya DuggalDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0001-5809-2081
Wendy S PostDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-8655-5204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndividuals with HIV have increased risk for coronary artery disease (CAD). However, the utility of the polygenic risk score (PRS) for estimating CAD risk (PRS

methodsA PRS

resultsPredicting the presence/absence of CAC in non-Hispanic White/genetically similar to European reference group adding PRS

conclusionsThe application of a PRS

Indexed as

Coronary Artery DiseaseCoronary VesselsHIV InfectionsMultifactorial InheritanceVascular CalcificationAdultAgedBlack or African AmericanComputed Tomography AngiographyCoronary AngiographyGenetic Predisposition to DiseaseHumansMaleMiddle AgedPredictive Value of TestsRisk Assessmentatherosclerosiscoronary artery calciumgenetic riskhuman immunodeficiency virus

Identifiers

PMID41220122
PMCPMC12887214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.