Evidence map›Paper›PMID 41219824›Full record

ArticleTropical diseases, travel medicine and vaccines2025

Atypical presentation of Lyme disease in a returning traveler: a case report.

Andrea S Salcedo, Xosse Carreras, Joe Saavedra, Sandy Saldaña, Nelson Diaz, Jose A Gonzales-Zamora, Jorge Alave

Abstract read
In one paragraph

Article in Tropical diseases, travel medicine and vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea S SalcedoSchool of Medicine, Universidad Peruana de Ciencias Aplicadas, Av Alameda San Marcos 11, Chorrillos, Lima, 15067, Peru.
Xosse CarrerasSchool of Medicine, Universidad Peruana de Ciencias Aplicadas, Av Alameda San Marcos 11, Chorrillos, Lima, 15067, Peru. xossecarreras@gmail.com.
Joe SaavedraSchool of Medicine, Universidad Peruana Union, Lima, Peru.
Sandy SaldañaSchool of Medicine, Universidad Peruana Union, Lima, Peru.
Nelson DiazSchool of Medicine, Universidad Peruana Union, Lima, Peru.
Jose A Gonzales-ZamoraPeruvian American Medical Society, Albuquerque, NM, USA.
Jorge AlaveSchool of Medicine, Universidad Peruana Union, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme disease, caused by Borrelia burgdorferi and transmitted by Ixodes ticks, is rare in South America and is often misdiagnosed in returning travelers. We report the case of a 19-year-old Peruvian male who presented with pruritic erythematous maculopapular lesions and abdominal pain after travel to Maryland, United State of America. His atypical cutaneous findings, including a crusted lesion with ill-defined borders and a maculopapular rash, were initially misinterpreted as bacterial cellulitis, resulting in multiple unsuccessful courses of antibiotics. Further evaluation, guided by his travel history, led to the diagnosis of Lyme disease through serological testing and histopathology. Treatment with doxycycline achieved complete resolution. This case illustrates the diagnostic challenges posed by atypical presentations of Lyme disease in nonendemic regions. Greater awareness among clinicians in South America is essential to recognize imported cases, facilitate early diagnosis, and prevent complications associated with delayed treatment.

Indexed as

Atypical skin lesionsBorrelia burgdorferiGlobal healthLyme diseaseTravel medicine

Identifiers

PMID41219824
PMCPMC12604217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.