Evidence map›Paper›PMID 41219704›Full record

ArticleBMC ophthalmology2025

Risk factors and predictive model for corneal edema in patients undergoing cataract surgery.

Ming-Wei Zheng

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Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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1 author.

Ming-Wei ZhengDepartment of Ophthalmology, The First Affiliated Hospital of Shantou University Medical College, Room 402, Building No.2, No.82 Jinsa Road, Shantou, 515000, China. 32607883@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the risk factors associated with developing corneal edema in patients undergoing cataract surgery and construct a predictive model based on the patient’s clinical characteristics.

methodsIn total, 502 patients who underwent cataract surgery at a tertiary hospital between January 2021 and December 2023 were included in this study. Multivariate logistic regression analysis was used to investigate risk factors for corneal edema. A prediction model was constructed, and its performance was evaluated using receiver operating characteristic (ROC) curve analysis. The model’s predictive performance was assessed using the area under the ROC curve (AUC).

resultsCorneal edema was observed in 393 patients after cataract surgery. Multivariate analysis revealed that advanced age (odds ratio [OR], 1.027; 95% confidence interval [CI]: 1.008–1.048; P = 0.007) was associated with an increased risk of corneal edema. Conversely, preoperative visual acuity ranged from 0.01 to 0.10 (OR: 0.476; 95% CI: 0.239–0.951; P = 0.035) and ≥ 0.10 (OR: 0.249; 95% CI: 0.141–0.437; P < 0.001), and intraoperative use of carbachol (OR: 0.378; 95% CI: 0.229–0.623; P < 0.001) were associated with a reduced risk of corneal edema. These combined factors predicted the risk of postoperative corneal edema in patients with cataract with an AUC of 71.5% (95% CI: 65.8%-77.1%; P < 0.001).

conclusionThis study’s findings revealed that a multivariate model based on patient age, preoperative visual acuity, and intraoperative use of carbachol can predict the risk of postoperative corneal edema in patients with cataract, demonstrating a moderate predictive value.

Indexed as

Cataract ExtractionCorneal EdemaPostoperative ComplicationsAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsROC CurveVisual AcuityCataract surgeryCorneal edemaPrediction modelRisk factors

Identifiers

PMID41219704
PMCPMC12606817

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