Evidence map›Paper›PMID 41219687›Full record

ArticleMagnetic resonance in medicine2026

Increasing Infusion Times of Hyperpolarized [1-

Paola Porcari, Vesselin Miloushev, Saket Patel, Thasin Peyear, Marjan Berishaj, Kayvan R Keshari

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Enhanced Glioblastoma Detection ThroughMagnetic resonance in medicine · 2026
    Article
  2. Article
  3. Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paola PorcariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Vesselin MiloushevDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Saket PatelDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Thasin PeyearDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Marjan BerishajDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Kayvan R KeshariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID https://orcid.org/0000-0002-5181-8035

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Leveraging fructose transport to create a privileged substrate to selectively fuel T cellsR01CA248364 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Kayvan R Keshari · 2021 to 2026
$4.3M
Development of large-field-of-view hyperpolarized MRIR01CA237466 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CUNNINGHAM, CHARLES H., HRICAK, HEDVIG · 2020 to 2024
$3.4M
Visualizing oxidative stress using hyperpolarized magnetic resonanceR01CA252037 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KESHARI, KAYVAN R · 2020 to 2024
$3.3M
Image-guided Trp-IDO/TDO-Kyn-AHR pathway inhibition, combined with immunotherapyR01CA249294 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KESHARI, KAYVAN R, MERGHOUB, TAHA · 2021 to 2025
$2.6M
GE Diamond DNP PolarizerS10OD016422 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2014 to 2014
$600k
Center for Molecular Imaging and Bioengineering (CMIB)NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA237466NCI NIH HHS R01 CA248364NCI NIH HHS R01 CA249294NCI NIH HHS R01 CA252037NIH HHS NIH R01CA237466NIH HHS P30CA008748NIH HHS R01CA248364NIH HHS R01CA249294NIH HHS R01CA252037NIH HHS S10 OD016422NIH HHS S10OD016422Sir Peter Michael FoundationThompson Family Foundation
6 · The paper itself

Abstract

purposeTo investigate whether varying delivery times of hyperpolarized [1-

methodsEighteen healthy mice were injected with 300 μL of hyperpolarized [1-

resultsThe mean FWHM values of the time-course curves of [1-

conclusionsIncreased delivery times of hyperpolarized [1-

Indexed as

BrainLactic AcidPyruvic AcidAnimalsCarbon IsotopesDeuterium OxideKineticsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiceMice, Inbred C57BLCarbon-13Carbon IsotopesDeuterium OxideLactic AcidPyruvic Aciddeuterium oxidehyperpolarized 13C‐pyruvateinjection timemurine brain

Identifiers

PMID41219687
PMCPMC12850587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.