SynthesisSpine deformity2026
Safety and efficacy of long spinal fusion to the pelvis for the treatment of neuromuscular scoliosis: single-arm meta-analysis and systematic review.
Synthesis in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
Abstract
STUDY
designSingle-arm meta-analysis and systematic review.
objectivesTo evaluate the safety and efficacy of pelvic fixation in the surgical treatment of neuromuscular scoliosis (NMS).
methodsA comprehensive search on PubMed, Embase and the Cochrane Library was performed to identify studies that included NMS treated with surgery. Changes in mean coronal curve angle (Cobb angle), pelvic obliquity (PO), thoracic kyphosis (TK), lumbar lordosis (LL), and other important surgical outcomes were evaluated and analyzed at baseline, postoperatively, and final follow-up. Surgical-related parameters and postoperative major complications were collected.
resultsA total of 29 studies comprising 1595 NMS patients were included in the meta-analysis. The mean operative time was 311.75 min, and the estimated blood loss was 1787.69 ml. The results demonstrated a significant reduction in the Cobb angle after surgery with pelvic fixation (mean reduction: 47.57°, 95% CI 43.04-52.10). PO was also significantly corrected (mean reduction: 13.71°, 95% CI 12.26-15.16). In addition, there was an improvement in TK (mean reduction: 7.42°, 95% CI 0.47-14.36) and an increase in LL (mean increase: 4.79°, 95% CI 9.73-0.16). Among the cohort of 1489 patients, 262 patients (17.6%) experienced implant-related complications, while 225 patients (15.1%) developed infections, neurological complications were observed in 7 patients (0.5%), revision surgeries were required for 86 patients (5.8%) and the overall mortality rate reached 0.7% (10 cases in total). These pooled radiographic corrections are clinically relevant to wheelchair sitting balance and overall spino-pelvic alignment in NMS, supporting pre-operative counseling about the functional value of pelvic fixation.
conclusionsPelvic fixation provides effective deformity and pelvic obliquity correction with acceptable complication rates. These pooled data offer benchmark reference values to guide surgical counseling and trial design.
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