Evidence map›Paper›PMID 41219636›Full record

ReviewAAPS PharmSciTech2025

A Review on Emerging Technologies in Pharmaceutical Packaging: From Anti-Counterfeiting to Green Solutions.

Krishang Sikaria, Amatha Sreedevi, Nandini Srivastava, Virendra S Ligade, Pradeep Muragundi, Sreedhar D

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krishang SikariaDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.ORCID http://orcid.org/0009-0000-5893-3338
Amatha SreedeviDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.ORCID http://orcid.org/0009-0008-2388-6488
Nandini SrivastavaDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.ORCID http://orcid.org/0009-0000-0618-8137
Virendra S LigadeDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.ORCID http://orcid.org/0000-0001-7945-3245
Pradeep MuragundiDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.ORCID http://orcid.org/0000-0003-4897-6187
Sreedhar DDepartment of Pharmaceutical Regulatory Affairs and Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India. d.sreedhar@manipal.edu.ORCID http://orcid.org/0000-0001-6325-4049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article discusses recent innovations and developments in pharmaceutical packaging and its emerging trends in five areas of priority: anti-counterfeiting, drug monitoring, drug quality preservation, sustainability, and patient compliance. The increasing problem of counterfeit medicine has raised the necessity of numerous security technologies to fight the issue. Physical-chemical identifiers, including inks, pigments, and molecular taggants, as well as overt and covert characteristics like holograms, colour-shifting inks, and digital watermarks, assist in verifying the authenticity of pharmaceutical products. New technologies such as carbon dots and microstructural markers in forensic inks add extra security against counterfeiting. Radio Frequency Identification technology assists in product condition tracking, minimizing medical errors, and enhancing patient safety across the supply chain. Colorimetric indicators, like time-temperature indicators and vaccine vial monitors, visually convey environmental conditions and preserve temperature-sensitive drugs' integrity. Drug quality and integrity is another area of importance discussed in the review. Novel packaging technologies, like dual-chamber delivery systems, multilayer constructions, and coatings, offer superior barrier properties and protection against degradation. The review also discusses increasing focus on eco-friendly packaging alternatives, including using renewable, biodegradable, and recycled materials to reduce the ecological footprint of drug packaging. Lastly, the article investigates the role of smart packaging technologies in patient compliance improvement through reminder systems, status indicators, and single-medicine storage units that assist patients in following the prescribed medication regime.

Indexed as

Counterfeit DrugsDrug PackagingGreen Chemistry TechnologyTechnology, PharmaceuticalHumansPharmaceutical PreparationsCounterfeit DrugsPharmaceutical PreparationsCounterfeitingPackaging technologyPatient compliancePharmaceutical packagingSustainability

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.