Evidence map›Paper›PMID 41219511›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Associations between maternal opioid use disorder treatment and pregnancy outcomes.

Mustafa Karakus, Rikki Welch, Meg Tucker, Tanvi Rao, Peter Lee, Cristian Ilie, Sushmita Shoma Ghose

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mustafa KarakusWestat, Rockville, MD, USA. mustafakarakus@westat.com.ORCID http://orcid.org/0000-0003-1200-3359
Rikki WelchWestat, Rockville, MD, USA.ORCID http://orcid.org/0009-0008-0500-8403
Meg TuckerWestat, Rockville, MD, USA.
Tanvi RaoWestat, Rockville, MD, USA.ORCID http://orcid.org/0009-0005-4197-3647
Peter LeeCareplots, Wayne, PA, USA.ORCID http://orcid.org/0009-0005-2962-8541
Cristian IlieCareplots, Wayne, PA, USA.ORCID http://orcid.org/0009-0008-6333-3634
Sushmita Shoma GhoseWestat, Rockville, MD, USA.

Funding

U.S. Department of Health and Human Services (U.S. Department of Health & Human Services) HHSS283201700031I/ 75S20322F42003U.S. Department of Health & Human Services | Substance Abuse and Mental Health Services Administration (SAMHSA) HHSS283201700031I/75S20322F42003
6 · The paper itself

Abstract

objectiveThis study examines associations between opioid use disorder (OUD) treatment and pregnancy outcomes among Medicaid enrollees. STUDY

designUsing 2021 Medicaid claims, we identified 29,193 women with OUD and a pregnancy-related outcome receiving (1) Medication Only, (2) Behavioral Therapy Only, (3) Medication and Behavioral Therapy, or (4) No Treatment. Multivariable logistic regression estimated adjusted odds ratios (ORs) for outcomes.

resultsAmong pregnant women with OUD, over half (52.5%) received no treatment; 27.9% received medication and therapy, 12.5% received medication only, and 7.0% received therapy only. Any form of treatment was linked to reduced risk of fetal death. Medication, alone or with therapy, was associated with lower risk of preterm labor, and medication alone was linked to reduced risk of abruptio placentae.

conclusionReceiving treatment for OUD is significantly associated with better pregnancy outcomes. Expanding access to medication for OUD and integrating therapy are crucial for improving maternal health.

Indexed as

Opiate Substitution TreatmentOpioid-Related DisordersPregnancy ComplicationsPregnancy OutcomeAdultFemaleHumansLogistic ModelsMedicaidPregnancyRetrospective StudiesUnited StatesYoung Adult

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.