Evidence map›Paper›PMID 41219210›Full record

ArticleNature communications2025

Graph-based pangenomes and pan-phenome provide a cornerstone for eggplant biology and breeding.

Luciana Gaccione, Laura Toppino, Marie Bolger, Maximilian Schmidt, Maria Rosaria Tassone, Maria Sulli, Emily Idahl, David Alonso, Giuseppe Aprea, Paola Ferrante and 14 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  4. From Lab to Field: CRISPRing Major CultivatedInternational journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Luciana GaccioneDISAFA, Plant Genetics, University of Turin, Grugliasco, TO, Italy.ORCID http://orcid.org/0000-0001-5194-0754
Laura ToppinoCREA, Research Centre for Genomics and Bioinformatics, Montanaso Lombardo, LO, Italy.
Marie BolgerIBG-4, CEPLAS, Forschungzentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0001-6335-1578
Maximilian SchmidtPlant Breeding Department, Geisenheim University, Geisenheim, Germany.
Maria Rosaria TassoneCREA, Research Centre for Genomics and Bioinformatics, Montanaso Lombardo, LO, Italy.ORCID http://orcid.org/0009-0003-3213-3078
Maria SulliENEA, Casaccia Res Ctr, Roma, Italy.
Emily IdahlFaculty for Mathematica and Natural Sciences, Institute for Biological Data Sciences, Heinrich Heine University, Düsseldorf, Germany.
David AlonsoUniversitat Politècnica de València, Valencia, Spain.
Giuseppe ApreaENEA, Casaccia Res Ctr, Roma, Italy.
Paola FerranteENEA, Casaccia Res Ctr, Roma, Italy.
Véronique LefebvreINRAE, GAFL, Montfavet, France.ORCID http://orcid.org/0000-0001-9916-8433
Hatice Filiz BoyaciFaculty of Agriculture, University of Recep Tayyip Erdogan, Rize, Türkiye.ORCID http://orcid.org/0000-0002-3799-4673
Roland SchafleitnerThe World Vegetable Center, Tainan City, Taiwan.ORCID http://orcid.org/0000-0003-3637-7603
Stefano GattolinNational Research Council of Italy, Institute of Agricultural Biology and Biotechnology (IBBA-CNR), Milan, Italy.ORCID http://orcid.org/0000-0003-3855-9160
Richard FinkersPlant Breeding, Wageningen University & Research WUR, Wageningen, The Netherlands.ORCID http://orcid.org/0000-0002-4368-8058
Matthijs BrouwerPlant Breeding, Wageningen University & Research WUR, Wageningen, The Netherlands.ORCID http://orcid.org/0000-0001-8183-0484
Arnaud BovyPlant Breeding, Wageningen University & Research WUR, Wageningen, The Netherlands.ORCID http://orcid.org/0000-0003-2643-7377
Jaime ProhensUniversitat Politècnica de València, Valencia, Spain.ORCID http://orcid.org/0000-0003-1181-9065
Ezio PortisDISAFA, Plant Genetics, University of Turin, Grugliasco, TO, Italy.
Sergio LanteriDISAFA, Plant Genetics, University of Turin, Grugliasco, TO, Italy.ORCID http://orcid.org/0000-0003-3012-8710
Giuseppe Leonardo RotinoCREA, Research Centre for Genomics and Bioinformatics, Montanaso Lombardo, LO, Italy.ORCID http://orcid.org/0000-0001-9138-0958
Giovanni GiulianoENEA, Casaccia Res Ctr, Roma, Italy. giovannigiuliano1@gmail.com.ORCID http://orcid.org/0000-0002-2486-0510
Björn UsadelIBG-4, CEPLAS, Forschungzentrum Jülich, Jülich, Germany. b.usadel@fz-juelich.de.ORCID http://orcid.org/0000-0003-0921-8041
Lorenzo BarchiDISAFA, Plant Genetics, University of Turin, Grugliasco, TO, Italy. lorenzo.barchi@unito.it.ORCID http://orcid.org/0000-0001-6414-4239

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101094738EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 677379
6 · The paper itself

Abstract

Eggplant (Solanum melongena L.) is a major Solanaceous crop of Asian origin, but genomic resources remain limited compared to related species. Here, a core collection of 368 accessions spanning global diversity of S. melongena and wild relatives is phenotyped for agronomic, disease resistance and fruit metabolomic traits and resequenced. Additionally, 40 chromosome-level assemblies of S. melongena, its progenitor S. insanum and the allied species S. incanum enable the construction of two graph-based pangenomes, capturing broad genetic variation. We demonstrate the power of these datasets by identifying major loci controlling prickliness and resistance to Fusarium oxysporum f. sp. melongenae, driven by SVs affecting the LONELY GUY 3 gene and a resistance gene cluster, respectively, as well as a mutation in a GDSL-like esterase/lipase gene altering the levels of dicaffeoyl-quinic acids. These findings provide a cornerstone for pangenome-assisted breeding, enabling detailed analyses of genetic diversity, domestication history, and trait evolution in eggplant.

Indexed as

Genome, PlantPlant BreedingSolanum melongenaDisease ResistanceFruitFusariumGenetic VariationGenomicsPhenotypePlant DiseasesQuantitative Trait Loci

Identifiers

PMID41219210
PMCPMC12606238

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.