Evidence map›Paper›PMID 41218767›Full record

ReviewOpen biology2025

Epstein-Barr virus functional RNAs as part of its immune evasion strategy: a role for EBER1?

Paul J Farrell

Abstract readReview
In one paragraph

Review in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Paul J FarrellSection of Virology, Imperial College London, London, UK.ORCID 0000-0002-6754-9351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several types of cancer and some auto-immune diseases are linked to Epstein-Barr virus (EBV) infection. In addition to viral proteins, EBV expresses many functional RNAs to influence cell biology, avoiding the immune responses that would be targeted to viral proteins. Some of these RNAs are also exported from the EBV-infected cells into surrounding cells, including those involved in immune surveillance of the EBV infected cells. EBER1 is the most abundant of these EBV RNAs and recent progress in understanding EBER1 mechanisms might make it a drug target for some diseases associated with EBV.

Indexed as

Epstein-Barr Virus InfectionsHerpesvirus 4, HumanImmune EvasionRNA, ViralAnimalsGene Expression Regulation, ViralHost-Pathogen InteractionsHumansEpstein-Barr virus encoded RNA 1RNA, ViralEBER1EBER2Epstein–Barr virusexosomemiRNARPL22

Identifiers

PMID41218767
PMCPMC12606207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.