ReviewJournal of advanced research2026
Transforming hosts into nurseries and nutrients: strategic manipulation by endoparasitoid wasps.
Review in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Review
- The role of a viral symbiont in the thermal mismatch of host-parasitoid interactions.The Journal of experimental biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasitoid wasps, shaped by ecological pressures and interspecific competition, have evolved sophisticated molecular strategies to manipulate host physiology, ensuring successful parasitism and optimal progeny development. Despite substantial advances in parasitoid-host interaction research, a systematic synthesis of these findings is still lacking. This review aims to consolidate recent findings on the molecular mechanisms by which endoparasitoids regulate host physiology, and to explore their potential applications in sustainable pest management. We reviewed recent progress on virulence factors derived from venom, polydnaviruses, and teratocytes, focusing on their roles in immune suppression, developmental regulation, and metabolic reprogramming of insect hosts. Three principal mechanisms underlying parasitoid-mediated host manipulation are identified: (1) Immune suppression: Parasitoids reduce hemocyte abundance, disrupt hemocyte mobilization to impede encapsulation, inhibit phenoloxidase activation to prevent melanization, and interfere with immune signaling pathways. Some species also adopt passive immune evasion strategies. (2) Developmental regulation: Parasitoids delay host growth and metamorphosis by downregulating ecdysteroid titers, inhibiting cell proliferation, degrading host tissues, and repressing protein synthesis. (3) Metabolic reprogramming: Parasitoids manipulate host amino acid, carbohydrate, and lipid metabolism to mobilize and redirect nutritional resources toward their developing offspring. This review offers a comprehensive overview of the molecular tactics employed by endoparasitoids to modulate host physiology. By elucidating these mechanisms, we propose parasitoid-derived virulence factors as promising leads for developing novel, sustainable pest control strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.