ReviewPLOS global public health2025
Tuberculosis laboratory capacity building in the WHO African Region: The past, the present and the future: A Viewpoint.
Review in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cross- Wellcome Africa Asian Programmes (AAPs) Acceleration of Genomics for Escalating infectious Diseases, (CAGED) Consortium.Wellcome open research · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis remains a leading infectious disease killer in the World Health Organization African Region, with 2.5 million cases and 404,000 deaths in 2023, including 112,000 people with HIV. There is slow progress with only 42% of the 75% targeted reduction in death by 2025. Out of 60,266 estimated multidrug-resistant TB cases in 2023, only 22,515 were notified. Laboratory diagnostic services in the African region still need urgent attention. By 2005, the new smear-positive case detection rate was nearly 51%, falling short of the 70% target. By 2015, the benchmark for one microscopy center per 100,000 population was reached in some Member States, but gaps remained in culture and drug susceptibility testing coverage. Molecular tests were adopted, however there is slow uptake among countries to use them as initial diagnostic tests. The Global Laboratory Initiatives were established in 2007 and 2013 globally and in the WHO African Region respectively to enhance access to quality-assured TB laboratory services. The WHO TB Supranational Reference Laboratory (SRL) Network was established in 1994 and expanded to the African region, including South Africa, Uganda, and Benin. The nomination of Mozambique and Rwanda in 2021 as candidate SRLs aims to strengthen this network. Future perspectives involve leveraging the established TB laboratory networks to integrate systems for diagnosing multiple diseases while enhancing efficiency. Advocacy for increased funding is vital for sustaining gains in the laboratory capacities, advancing universal health coverage and enhancing health outcomes in the African region. Here we discuss the TB laboratory capacity building in the WHO African region, focusing on the past, present and the future perspectives. We suggest recommendation towards sustaining and strengthening the existing achievements, while accelerating the laboratory interventions towards the End TB Strategy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.