Evidence map›Paper›PMID 41217788›Full record

ArticleJournal of Parkinson's disease2026

A modified Delphi study of post-operative management for subthalamic deep brain stimulation in Parkinson's disease.

Anna J Pedrosa, Jan-Niklas Molter, Leonardo Brito de Almeida, Katsuo Kimura, Tiago Mestre, Michael S Okun, Philipp Capetian, David J Pedrosa

Abstract read
In one paragraph

Article in Journal of Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna J PedrosaDepartment of Neurology, Philipps University Marburg, University Hospital Giessen and Marburg, Marburg, Germany.ORCID 0000-0002-4757-9019
Jan-Niklas MolterDepartment of Neurology, Philipps University Marburg, University Hospital Giessen and Marburg, Marburg, Germany.ORCID 0009-0000-7220-2814
Leonardo Brito de AlmeidaDepartment of Neurology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-0921-887X
Katsuo KimuraDepartment of Neurology, Yokohama City University Medical Center, Yokohama, Japan.ORCID 0000-0002-3339-8743
Tiago MestreParkinson's Disease and Movement Disorders Center, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa Brain and Mind Institute, Ottawa, Canada.ORCID 0000-0002-6973-7479
Michael S OkunDepartment of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-6247-9358
Philipp CapetianDepartment of Neurology, University Hospital and Julius-Maximilians-University, Wuerzburg, Germany.ORCID 0000-0003-1712-3659
David J PedrosaDepartment of Neurology, Philipps University Marburg, University Hospital Giessen and Marburg, Marburg, Germany.ORCID 0000-0002-5403-1959

Funding

Defining Targets for Tic Detection and Suppression in Tourette Syndrome Deep Brain StimulationUH3NS119844 · NINDS · UNIVERSITY OF FLORIDA · PI BUTSON, CHRISTOPHER R, GUNDUZ, AYSEGUL · 2021 to 2025
$5.0M
Web-based Automated Imaging Differentiation of ParkinsonismU01NS119562 · NINDS · UNIVERSITY OF FLORIDA · PI BARMPOUTIS, ANGELOS, OKUN, MICHAEL S · 2021 to 2025
$4.8M
Mobile Decision Support System for Nurse Management of Neuromodulation TherapyR01NR014852 · NINR · UNIVERSITY OF UTAH · PI BUTSON, CHRISTOPHER R, OKUN, MICHAEL S · 2015 to 2019
$2.9M
THE HUMAN THALAMOCORTICAL NETWORK IN TOURETTE SYNDROMER01NS096008 · NINDS · UNIVERSITY OF FLORIDA · PI GUNDUZ, AYSEGUL, OKUN, MICHAEL S · 2016 to 2020
$1.8M
University of Florida R25 Early Research Program for Neurology and Neurosurgery ResidentsR25NS108939 · NINDS · UNIVERSITY OF FLORIDA · PI HOH, BRIAN LIM, HOH, BRIAN LIM · 2019 to 2024
$537k
NINDS NIH HHS R01 NS096008NINDS NIH HHS R25 NS108939NINDS NIH HHS U01 NS119562NINDS NIH HHS UH3 NS119844NINR NIH HHS R01 NR014852
6 · The paper itself

Abstract

BackgroundDespite the widespread adoption of deep brain stimulation (DBS) for treating Parkinson's disease (PD) over the last few decades, standardized post-operative care protocols remain lacking.ObjectiveThis study aimed to establish expert consensus on managing post-operative subthalamic nucleus (STN-DBS).MethodsA three-round online Delphi study was conducted involving an international panel of DBS experts actively engaged in all facets of post-operative care. In the initial round, the panel generated ideas regarding essential components of a post-operative care protocol. In rounds two and three, numerical ratings and rankings were employed to achieve consensus on the formulated statements. This iterative process culminated in a refined STN-DBS care protocol.ResultsThe study included 76 international participants who, over three survey rounds, reached consensus on 129 components of a care protocol for managing post-operative STN-DBS. The final protocol encompassed eleven essential domains: hospital discharge, rehabilitation referral, imaging and lead review, monopolar testing, local field potential sensing, troubleshooting, medication management, multiprofessional care, follow-up, empowerment of patients and caregivers, and quality control of management procedures.ConclusionsThis Delphi-based, expert-driven process resulted in a comprehensive care protocol for patients undergoing STN-DBS. The findings offer a valuable resource for healthcare professionals, providing a structured, consensus-based framework aimed at optimizing post-operative outcomes. In addition to supporting clinical practice, these recommendations may help inform policy development and drive systematic improvements in care delivery. Further research and validation in diverse clinical settings will be essential to assess the generalizability and real-world impact of the proposed procedures.

Indexed as

ConsensusDeep Brain StimulationParkinson DiseasePostoperative CareSubthalamic NucleusDelphi TechniqueHumansaftercarecare pathwaysdeep brain stimulationhealth care quality assuranceParkinson's disease

Identifiers

PMID41217788
PMCPMC13347560

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.