Evidence map›Paper›PMID 41217715›Full record

ArticleJournal of assisted reproduction and genetics2026

Magnitude of Post-Retrieval Estradiol Decline Directly Compromises Clinical Pregnancy and Live Birth Rates in High Responders Undergoing IVF/ICSI cycles with antagonist protocols.

Qianqian Chen, Yanbo Du, Xu Han, Mei Sun

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qianqian ChenState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.
Yanbo DuState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.
Xu HanState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.
Mei SunState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. sunmei0531@163.com.ORCID http://orcid.org/0009-0008-1431-2482

Funding

Shandong Medical and Health Science and Technology Project 202405030879
6 · The paper itself

Abstract

purposeTo investigate whether the magnitude of estradiol (E

methodsThis retrospective cohort study analyzed 1859 fresh embryo transfer cycles (high responders, January 2018-December 2021) under antagonist protocols. Final oocyte maturation was triggered with GnRHa, hCG, or dual trigger. Serum E

resultsMean patient age was 31.0 years; 82.0% involved day 3 transfers. Overall CPR and LBR were 56.2% and 45.2%, respectively. The low E

conclusionA post-retrieval E

Indexed as

EstradiolFertilization in VitroSperm Injections, IntracytoplasmicAdultBirth RateChorionic GonadotropinEmbryo TransferFemaleGonadotropin-Releasing HormoneHumansLive BirthOocyte RetrievalOvulation InductionPregnancyPregnancy RateRetrospective StudiesChorionic GonadotropinEstradiolGonadotropin-Releasing HormoneAntagonist protocolEstrogenFresh embryo transferIVF/ICSIPregnancy outcomes

Identifiers

PMID41217715
PMCPMC12901751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.