Evidence map›Paper›PMID 41217252›Full record

ArticleJournal of medicinal chemistry2025

Jakub Zýka, Jaroslav Kozák, Lenka Vanekova, Marketa Pimkova Polidarova, Vít Prouza, Nina Habanová, Timotej Strmeň, Martin Zavřel, Petr Pachl, Jan Choutka and 4 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jakub ZýkaGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Jaroslav KozákGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Lenka VanekovaDepartment of Genetics and Microbiology, Faculty of Science, BIOCEV, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic.
Marketa Pimkova PolidarovaDepartment of Genetics and Microbiology, Faculty of Science, BIOCEV, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic.
Vít ProuzaGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Nina HabanováGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.ORCID 0000-0001-6412-9901
Timotej StrmeňGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Martin ZavřelGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.ORCID 0000-0003-4740-876X
Petr PachlGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Jan ChoutkaGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.ORCID 0000-0001-6290-9787
Klara Grantz SaskovaDepartment of Genetics and Microbiology, Faculty of Science, BIOCEV, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic.ORCID 0000-0003-2874-5699
Andrea BrazdovaDepartment of Genetics and Microbiology, Faculty of Science, BIOCEV, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic.
Kamil ParkanGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.
Radek PohlGilead Sciences & IOCB Research Centre, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, 166 10 Prague, Czech Republic.ORCID 0000-0001-7898-946X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Galectin-3 (Gal-3) is a galactose-binding lectin involved in pathologies such as inflammation, fibrosis, heart disease, and tumor progression. Here, we report

Indexed as

Antifibrotic AgentsGalectin 3Blood ProteinsCell LineHepatic Stellate CellsHumansStructure-Activity RelationshipAntifibrotic AgentsBlood ProteinsGalectin 3

Identifiers

PMID41217252
PMCPMC12670426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.