Evidence map›Paper›PMID 41217214›Full record

ArticleThe Journal of organic chemistry2025

Unanticipated Reactivity toward Nucleophilic Attack in the Synthesis of Saccharyl-1,3,4-Thiadiazolyl Conjugates: Structure and Mechanistic Insights.

Bruno E C Guerreiro, Daniel F Carvalho, Jaime A S Coelho, José A Paixão, Luís M T Frija, Maria L S Cristiano

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruno E C GuerreiroCentro de Ciências do Mar (CCMAR), and Department of Chemistry and Pharmacy (FCT), University of Algarve, Campus de Gambelas, P-8005-039 Faro, Portugal.ORCID 0000-0001-7219-7939
Daniel F CarvalhoInstitute of Molecular Sciences (IMS), Centro de Química Estrutural (CQE), Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016 Lisboa, Portugal.
Jaime A S CoelhoInstitute of Molecular Sciences (IMS), Centro de Química Estrutural (CQE), Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016 Lisboa, Portugal.ORCID 0000-0002-7459-0993
José A PaixãoCFisUC, Department of Physics, University of Coimbra, 3004-516 Coimbra, Portugal.ORCID 0000-0003-4634-7395
Luís M T FrijaInstitute of Molecular Sciences (IMS), Centro de Química Estrutural (CQE), Instituto Superior Técnico, University of Lisbon, 1049-001 Lisboa, Portugal.
Maria L S CristianoCentro de Ciências do Mar (CCMAR), and Department of Chemistry and Pharmacy (FCT), University of Algarve, Campus de Gambelas, P-8005-039 Faro, Portugal.ORCID 0000-0002-9447-2855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Along with the synthetic process optimization of 3-[(5-methyl-1,3,4-thiadiazole-2-yl)sulfanyl]-1,2-benzothiazole 1,1-dioxide (MTSB), a selective copper chelator with potential interest in cancer chemotherapy, the unprecedented isolation of a novel compound, 3-(1,1-dioxidobenzo[

Identifiers

PMID41217214
PMCPMC12818759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.