Evidence map›Paper›PMID 41216908›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Physical exercise training improves muscle strength and self-esteem in children with intestinal failure.

Rozemarijn Duister, Emma Koster, Leontien Toussaint-Duyster, Mandy van Drunen, Carina Klees, Jessie Hulst, Edmond Rings, Rene Wijnen, Barbara de Koning, Linda van den Berg

Abstract readControlled Clinical Trial
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rozemarijn DuisterDepartment of Pediatric Gastroenterology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID https://orcid.org/0009-0001-8294-1853
Emma KosterDepartment of Internal Medicine, Division of Dietetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Leontien Toussaint-DuysterDepartment of Orthopedics and Sports Medicine, Unit Physical Therapy, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Mandy van DrunenDepartment of Orthopedics and Sports Medicine, Unit Physical Therapy, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Carina KleesDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Jessie HulstDivision of Gastroenterology. Hepatology and Nutrition, the Hospital for Sick Children, Toronto, Ontario, Canada.
Edmond RingsDepartment of Pediatric Gastroenterology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Rene WijnenDepartment of Pediatric Surgery, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Barbara de KoningDepartment of Pediatric Gastroenterology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Linda van den BergDepartment of Orthopedics and Sports Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

Funding

Maag-Darm-Lever Fonds, Janivo, and van Herk Foundation
6 · The paper itself

Abstract

objectivesPediatric intestinal failure (IF) patients are less physically active compared to healthy peers, exhibit an altered body composition and low bone mineral density, which can be improved through physical activity. We assessed the effects of a tailored exercise intervention on physical fitness, nutritional status, and psychological functioning in children with IF.

methodsPediatric IF patients, still on and weaned off parenteral nutrition aged 6-18 years were eligible. Physical fitness ([sub]maximal exercise capacity, amount of physical activity, motor performance, strength, and core stability), nutritional status (body composition, energy expenditure, and laboratory parameters) and psychological functioning (fear, quality of life, fatigue, gastrointestinal symptoms, and self-esteem) were assessed before and after an initial control period and after a 12-week tailored exercise intervention.

resultsSixteen participants (median age 12.2 years [10.5-14.6]) underwent baseline assessments, and eight were weaned off parenteral nutrition. Exercise capacity was normal, but the majority (63%) did not meet physical activity guidelines. Motor skills and muscle strength were impaired. Postintervention, exercise capacity in VO

conclusionsOur tailored exercise intervention improved muscle strength, core stability, and self-esteem. Most participants do not meet physical activity recommendations and exhibit impaired muscle strength and motor skills, while exercise capacity is normal. Notably, participants with better baseline motor skills showed greater improvements in exercise capacity. CLINICAL

trial registrationRegistration ID: NL8181, https://onderzoekmetmensen.nl/nl/trial/27466.

Indexed as

ExerciseExercise TherapyIntestinal FailureMuscle StrengthSelf ConceptAdolescentChildFemaleHumansMaleNutritional StatusPhysical FitnessQuality of Lifeinterventionparenteral nutritionpediatrics

Identifiers

PMID41216908
PMCPMC12780475

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.