Evidence map›Paper›PMID 41216891›Full record

ReviewJournal of investigative medicine high impact case reports

ALK-Negative Anaplastic Large Cell Lymphoma With Rare Scalp Involvement: A Case Report and Literature Review.

Jamal Abdallah, Maaweya Jabareen, Wasef Alhroub, Muntaser S Ahmad, Ziad Risheq, Mohammad Aqel, Hani Hour, Roa'a Halaykh, Majd Amleh, Isra Hamoudah and 2 more

Abstract readCase ReportsReview
In one paragraph

Review in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jamal AbdallahHebron University, Palestinian Territory.ORCID 0009-0009-4533-6919
Maaweya JabareenHebron University, Palestinian Territory.ORCID 0009-0002-5911-6705
Wasef AlhroubHebron University, Palestinian Territory.ORCID 0009-0007-1721-0038
Muntaser S AhmadAl-Ahli Hospital, Hebron, Palestinian Territory.
Ziad RisheqAl-Ahli Hospital, Hebron, Palestinian Territory.
Mohammad AqelAl-Hussein Governmental Hospital, Beit Jala, Palestinian Territory.
Hani HourAl-Quds University, Abu Dis, Palestinian Territory.ORCID 0000-0002-0561-4517
Roa'a HalaykhHebron University, Palestinian Territory.
Majd AmlehHebron University, Palestinian Territory.
Isra HamoudahHebron University, Palestinian Territory.ORCID 0009-0000-7313-4235
Alaa JanazerahMansoura University, Egypt.ORCID 0009-0004-9599-3371
Akram KaramaAl-Quds University, Abu Dis, Palestinian Territory.ORCID 0009-0009-0160-3886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplastic large-cell lymphoma (ALCL) is a rare type of T-cell lymphoma characterized by a clonal proliferation of atypical large cells. Here, we describe a 63-year-old man presenting with subcutaneous nodules on the scalp and anterior chest wall, right axillary lymphadenopathy, and systemic B symptoms. Positron emission tomography imaging revealed hypermetabolic activity in the scalp, chest wall, and axillary lymph nodes, suggestive of aggressive lymphoma. Histopathological analysis confirmed lymphoma with atypical large cells, and immunohistochemistry showed that both ALK and CD30 were negative, making the diagnosis atypical. This case illustrates the rarity of scalp involvement in ALK-negative ALCL and underscores the importance of a multidisciplinary approach, integrating clinical, imaging, and histological findings for accurate diagnosis and management.

Indexed as

Lymphoma, Large-Cell, AnaplasticScalpSkin NeoplasmsAnaplastic Lymphoma KinaseHumansImmunohistochemistryLymph NodesMaleMiddle AgedPositron-Emission TomographyALK protein, humanAnaplastic Lymphoma Kinaseaggressive lymphomaALK-negative ALCLCD30-negativescalp involvementT-cell lymphoma

Identifiers

PMID41216891
PMCPMC12605880

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.