Evidence map›Paper›PMID 41216824›Full record

ArticleOrganic letters2025

Hydrophilic BIPHEPHOS Ligand for Pd-Mediated Cysteine Allylation of Peptides and Proteins in Water.

Thomas Schlatzer, Julia Kriegesmann, Mark Bieber, Christian F W Becker, Rolf Breinbauer

Abstract read
In one paragraph

Article in Organic letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas SchlatzerInstitute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.ORCID 0000-0001-5034-0968
Julia KriegesmannInstitute of Biological Chemistry, Faculty of Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.
Mark BieberInstitute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
Christian F W BeckerInstitute of Biological Chemistry, Faculty of Chemistry, University of Vienna, Währinger Strasse 38, A-1090 Vienna, Austria.ORCID 0000-0002-8890-7082
Rolf BreinbauerInstitute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.ORCID 0000-0001-6009-7359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selective and natural post-translational modification of peptides and proteins under biocompatible conditions remains a challenge. Herein, we report a hydrophilic variant of the BIPHEPHOS ligand featuring diethyl phosphonates as solubilizing groups, which were found to be catalytically isofunctional to unpolar

Indexed as

CysteinePalladiumPeptidesProteinsCatalysisHydrophobic and Hydrophilic InteractionsLigandsMolecular StructureWaterCysteineLigandsPalladiumPeptidesProteinsWater

Identifiers

PMID41216824
PMCPMC12645573

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.