ReviewJournal of experimental botany2026
Cell-to-cell connectivity: a future target for crop improvement.
Review in Journal of experimental botany, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Improved mesophyll-bundle sheath connectivity is achieved via different mechanisms in CThe New phytologist · 2026Article
- Plasmodesmata.Journal of experimental botany · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Boosting crop productivity while enhancing resilience to climate change and disease remains a major challenge. Plasmodesmata (PD), which mediate cell-to-cell connectivity, are crucial for plant growth but remain underutilized as targets for crop improvement. This review focuses on C4 photosynthesis to demonstrate the importance of enhanced cell-to-cell connectivity to improve productivity. In C4 plants, connectivity between mesophyll (M) and bundle sheath (BS) cells is essential for building an efficient CO2-concentrating mechanism. Enhanced PD frequency at the M-BS interface is a key feature of C4 Kranz leaf anatomy, and thus an important trait to introduce in engineering C4 photosynthesis into C3 crops. We propose potential gene targets to engineer PD connectivity, while emphasizing the need for further research to discover new targets that affect PD formation and regulation. We also discuss advances in biotechnological tools that are important for both molecular studies and deploying strategies to manipulate PD in crops. These target genes and tools may ultimately unlock new capabilities to improve crop productivity and resilience by engineering cell-to-cell connectivity within various tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.