Evidence map›Paper›PMID 41216647›Full record

ArticleEuropean journal of orthodontics2025

Release of monomers in patient saliva following bonding of orthodontic brackets.

Håkon Gulliksen, Hilde M Kopperud, Marit Midtbø, Hanne Wellendorf, Nils Roar Gjerdet

Abstract read
In one paragraph

Article in European journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Håkon GulliksenPrivate Orthodontic Practice, Stord Tannregulering AS, Hamnegata 2, NO 5411 Stord, Norway.ORCID 0009-0006-1884-8685
Hilde M KopperudNordic Institute of Dental Materials (NIOM), Sognsveien 70A, NO 0855 Oslo, Norway.ORCID 0009-0002-0781-3904
Marit MidtbøPrivate Orthodontic Practice, Midtbø Tannregulering, Bøneslien 49, NO 5155 Bønes, Norway.ORCID 0009-0002-8431-3612
Hanne WellendorfNordic Institute of Dental Materials (NIOM), Sognsveien 70A, NO 0855 Oslo, Norway.ORCID 0009-0006-5049-6392
Nils Roar GjerdetFaculty of Medicine, Department of Clinical Dentistry, University of Bergen, Årstadveien 19, NO 5009 Bergen, Norway.ORCID 0000-0003-4019-3946

Funding

University of Bergen
6 · The paper itself

Abstract

introductionThis study aimed to investigate whether orthodontic treatment with fixed appliances increased concentration of various monomers in patients' saliva.

methodsThe study included 30 patients aged 10-18. Saliva samples were collected at three time points: before the start of active treatment, immediately after the bonding of orthodontic brackets and during the first follow-up visit between 4 and 6 weeks after bonding. Gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) were employed to analyse the samples.

resultsMeasurable levels of poly-EGDMA, HEMA, and BMAEPH were detected in saliva samples collected immediately after bracket bonding. Concentrations varied among patients. However, these substances were not quantifiable in saliva 4-6 weeks after bracket placement.

conclusionsThe bonding of orthodontic brackets is associated with a transient increase in the concentration of bonding material constituents in saliva immediately after placement. The findings suggest that, using the current analytical methods, this release is temporary.

Indexed as

Dental BondingOrthodontic BracketsSalivaAdolescentChildChromatography, LiquidFemaleGas Chromatography-Mass SpectrometryHumansMaleMethacrylatesResin CementsMethacrylatesResin Cementsbracketschemical analysismonomer releaseorthodontic bondingsaliva

Identifiers

PMID41216647
PMCPMC12603559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.