Evidence map›Paper›PMID 41216633›Full record

ReviewInternational journal of MCH and AIDS2025

Effectiveness of Human Immunodeficiency Virus Index Testing: A Global Scoping Review.

Abhiruchi Galhotra, Sanjana Agrawal, Aditi Chandrakar

Abstract readReview
In one paragraph

Review in International journal of MCH and AIDS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abhiruchi GalhotraDepartment of Community and Family Medicine, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.ORCID https://orcid.org/0000-0001-6169-8527
Sanjana AgrawalIndependent Public Health Researcher, Raigarh, Chhattisgarh, India.ORCID https://orcid.org/0000-0002-0274-2193
Aditi ChandrakarDepartment of Community and Family Medicine, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Over 2.5 million people are living with human immunodeficiency virus (HIV) in India. The World Health Organization recommends HIV self-screening and partner notification services. Index testing is a case-finding approach that focuses on eliciting the sexual or needle-sharing partners and biological children of HIV-positive individuals. This review aims to understand the effectiveness of index case testing in the uptake of HIV diagnosis and care. Methods: A scoping review was conducted to examine the effectiveness of HIV index case testing. Studies published between 2010 and 2024 in English were included. A total of 10 final studies were included in this scoping review. No such studies were found in the Indian context. Results: The studies were from Zimbabwe, Malawi, Nigeria, South Africa, Lesotho, Kenya, Zambia, Mozambique, and Ukraine. Sample sizes ranged from under 1,000 individuals to large-scale community-based programs enrolling over 38,000 participants. The studies demonstrated the effectiveness of index case testing in identifying previously undiagnosed HIV infections among sexual partners (up to 51%) and children (4.0-5.8%) of people living with HIV. The studies also indicated high acceptance rates and feasibility of the approach. Conclusion and Global Health Implications: HIV index case testing presents a valuable strategy for reaching diverse populations at risk for HIV infection and improving care linkages. Further research is needed to explore cost-effectiveness and optimize implementation strategies for various contexts.

Indexed as

Contact TracingHIV TestingHuman Immunodeficiency VirusIndex Case TestingLinkage to Care

Identifiers

PMID41216633
PMCPMC12596807

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.