Evidence map›Paper›PMID 41216622›Full record

ArticleEndoscopy international open2025

Image-enhanced endoscopy improves visibility of endoscopic images in individuals with color vision deficiency.

Akiko Ohno, Jun Miyoshi, Mitsunori Kusuhara, Yoko Jinbo, Ryosuke Kaji, Takahiro Shirakawa, Moegi Watanabe, Shiori Tsubata, Ryutaro Sumi, Minoru Matsuura and 3 more

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In one paragraph

Article in Endoscopy international open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akiko OhnoDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.ORCID 0000-0002-2271-5141
Jun MiyoshiDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Mitsunori KusuharaDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.ORCID 0000-0002-2918-4806
Yoko JinboDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Ryosuke KajiDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Takahiro ShirakawaDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Moegi WatanabeDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Shiori TsubataDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Ryutaro SumiDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Minoru MatsuuraDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.
Koichi IgaColor Universal Design Organization, Tokyo, Japan.
Masataka OkabeDepartment of Anatomy, Jikei University School of Medicine, Minato, Japan.
Tadakazu HisamatsuDepartment of Gastroenterology and Hepatology, Kyorin University, Tokyo, Japan.ORCID 0000-0002-1178-3536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Color vision deficiency (CVD) may affect perception of color information in gastrointestinal endoscopy. However, the color-universal concept in endoscopy remains underappreciated. We hypothesized that image-enhanced endoscopy (IEE) could improve object/lesion visibility regardless of CVD and tested this hypothesis with volunteers of varying color vision characteristics. Methods: Sixty objects/lesions (20 each of submucosal vessels during colorectal endoscopic submucosal dissection, superficial esophageal cancer, and early gastric cancer) were evaluated. Images with WLI and IEE (red dichromatic imaging [RDI], narrow-band imaging [NBI], or indigo carmine) were assessed for each object/lesion. Twenty evaluators (9 with general color vision: Type C and 11 with two types of CVD [7 with protanopia: Type P and 4 with deuteranopia: Type D]) scored vessel and lesion visibility using a four-level scale. Results: RDI significantly improved the visibility of submucosal vessels in Types P and D ( Conclusions: IEE improves visibility of objects/lesions where color information plays a role in detection, regardless of CVD.

Indexed as

Diagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE)Endoscopy Lower GI TractEndoscopy Upper GI TractQuality and logistical aspectsQuality management

Identifiers

PMID41216622
PMCPMC12597084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.