Evidence map›Paper›PMID 41216361›Full record

ArticleWellcome open research2025

Linking behaviour change techniques to mechanisms of action: Using the Theory and Techniques Tool alongside the Behaviour Change Intervention Ontology.

Lisa Zhang, Paulina M Schenk, Micaela Santilli, Alison J Wright, Marta M Marques, Marie Johnston, Robert West, Susan Michie

Abstract read
In one paragraph

Article in Wellcome open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lisa Zhang *Centre for Behaviour Change, University College London, London, England, UK.ORCID https://orcid.org/0000-0002-4255-9609
Paulina M Schenk *Centre for Behaviour Change, University College London, London, England, UK.ORCID https://orcid.org/0000-0002-5239-1977
Micaela SantilliCentre for Behaviour Change, University College London, London, England, UK.ORCID https://orcid.org/0009-0000-2740-8231
Alison J WrightInstitute of Pharmaceutical Science, King's College London, London, England, UK.ORCID https://orcid.org/0000-0002-0373-5219
Marta M MarquesNOVA National School of Public Health, Comprehensive Health Research Centre (CHRC), NOVA University of Lisbon, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-4797-9557
Marie JohnstonAberdeen Health Psychology Group, University of Aberdeen, Aberdeen, Scotland, UK.ORCID https://orcid.org/0000-0003-0124-4827
Robert WestCentre for Behaviour Change, University College London, London, England, UK.ORCID https://orcid.org/0000-0001-6398-0921
Susan MichieCentre for Behaviour Change, University College London, London, England, UK.ORCID https://orcid.org/0000-0003-0063-6378

Funding

Advancing Prevention Research In Cancer through Ontology Tools (The APRICOT project) Project Narrative U01CA291884 · NCI · UNIVERSITY COLLEGE LONDON · PI Susan Michie · 2024 to 2026
$1.4M
NCI NIH HHS U01 CA291884Wellcome Trust
6 · The paper itself

Abstract

Background: Understanding how interventions work requires clear hypotheses, rigorous testing, and accurate reporting of links between behaviour change techniques (BCTs)-the smallest replicable active components of interventions-and mechanisms of action (MoAs), the processes through which behaviour changes. The Theory and Techniques Tool (TaTT) provides a grid of likely BCT-MoA links to guide intervention design, based on literature synthesis and expert consensus. Recently, the Behaviour Change Intervention Ontology development team introduced detailed, computer-readable lower-level ontologies for BCTs and MoAs, but limited guidance exists on integrating the BCT-MoA links proposed by the TaTT with these ontologies. This study aimed to map BCTs and MoAs from the TaTT to corresponding classes (i.e., categorisations or groupings) in the Behaviour Change Technique Ontology (BCTO) and Mechanism of Action (MoA) Ontology. Methods: Three researchers mapped the classes from the BCTO onto 74 BCTs within the TaTT, using their definitions. Similarly, two researchers mapped classes from the MoA Ontology onto the 26 MoAs within the TaTT. Discrepancies were resolved through discussion with senior researchers. Subsequent updates to the BCT and MoA Ontologies necessitated a researcher updating the mappings, with the revisions being verified by the research team. Results: From the BCTO, 85 BCTs were mapped to the 74 BCTs present in the TaTT, while 56 MoAs from the MoA Ontology were mapped to the 26 MoAs present in the TaTT. Subclasses of these 85 BCTs and 56 MoAs provide additional specificity and can be found by further engaging with these ontologies. Discussion: Mapping the TaTT to the Behaviour Change Intervention Ontology enhances clarity and precision in selecting and reporting BCT-MoA links, enabling integration of data across frameworks. Future work should maintain these mappings as ontologies evolve and users provide more feedback and evidence on BCTs, MoAs and their links, ensuring they remain relevant and user-friendly.

Indexed as

behaviour change; intervention; ontology; theory; mechanisms of action; behaviour change techniques

Identifiers

PMID41216361
PMCPMC12596556

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.