ArticleEuropean heart journal. Imaging methods and practice2025
Normal reference intervals for left atrial volume and cardiac dimensions according to age and sex assessed by two different methods using cardiac computed tomography angiography.
Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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10 authors.
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Abstract
Aims: Left atrial volume (LAV) is a recognized prognostic marker of cardiovascular events. However, normal LAV thresholds on cardiac computed tomography angiography (CCTA) remain poorly defined, and the optimal assessment method is unclear. Our aim was to determine normal reference values of maximal systolic LAV (LAVmax) and ventricular dimensions normalized by age, sex, and body surface area (BSA) from CCTA by using dedicated semi-automated analysis software. Methods and results: This single-centre retrospective study included 250 healthy subjects with no cardiac history or significant CCTA abnormalities, stratified by sex and age. LAVmax was measured using both 3D and area-length methods, and all other cardiac chambers were analysed with dedicated 3D semi-automated software (Vitrea Conclusion: Indexed LAVmax was not significantly different across sexes but increased with age. LAVmax can be reliably reported from CCTA datasets, with 3D volumetric method providing the largest and most reproducible values. Normal values for all cardiac chambers according to age categories and sex were also provided. These normative values enhance the clinical utility of routine CCTA beyond coronary imaging.
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