ArticleOncoTargets and therapy2025
Decoding the Prognosis-Related S100A9
Article in OncoTargets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Monocytes and macrophages are recognized as predominant immune populations in human glioblastoma, where they play vital roles in tumor progression. Despite their established significance, the heterogeneity of these cells-particularly within the monocyte compartment-remains incompletely characterized. Methods: We comprehensively used scRNA-seq, spatial transcriptome sequencing combined with immunofluorescence and T cell co-culture assays to illuminate the heterogeneity and function of monocyte in glioblastoma. Results: In this study, from the perspective of ligand-receptor networks, we have identified and characterized three distinct glioblastoma subtypes. Single-cell RNA-seq analysis further revealed that the C3 subtype with bad prognosis exhibited a higher proportion of S100A9 Conclusion: In summary, our results deciphered the heterogeneity of monocytes in glioblastoma and identified a novel poor prognosis-associated monocyte subset, S100A9
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Registered trials
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