Evidence map›Paper›PMID 41216289›Full record

ArticleFrontiers in genetics2025

Identification and functional analysis of a novel

Nannan Zhang, Miao Han, Tong Zhao, Xinxin Tang, Zhiwei Wang, Yunqiu Du, Leilei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nannan Zhang *Department of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Miao Han *Department of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Tong ZhaoDepartment of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Xinxin TangDepartment of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Zhiwei WangDepartment of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Yunqiu DuDepartment of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.
Leilei WangDepartment of Prenatal Diagnosis, Lianyungang Maternal and Child Health Hospital of Yangzhou University, Lianyungang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Casein Kinase II Subunit Alpha (CK2α), the catalytic subunit of protein kinase CK2, is encoded by Methods: Clinical data and fetal umbilical cord blood samples were collected. Whole-genome sequence (WGS) was used for potential pathogenic variants identification, followed by Sanger sequencing to validate the variant. Bioinformatic tools were employed to predict the 3D structure of the variant. Wild-type and mutant Result: A 33-year-old pregnant woman without adverse obstetric history. At 34 Conclusion: We report a novel

Indexed as

CSNK2A1 genegene variantintracranial abnormalityStillbirhWGSwhole-genome sequencing

Identifiers

PMID41216289
PMCPMC12597092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.