Evidence map›Paper›PMID 41216181›Full record

ArticleIDCases2025

A case report of Staphylococcus saccharolyticus bloodstream infection in a non-implanted host diagnosed by mNGS: Mechanism and pathogenesis analysis.

Ziwen Song, Tingting Huang, Xi Jiang, Ming Hu, Hui Wu, Jiaping Wang

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ziwen SongDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.
Tingting HuangDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.
Xi JiangDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.
Ming HuDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.
Hui WuDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.
Jiaping WangDepartment of Clinical Laboratory, Donghai County People's Hospital/Affiliated Donghai Hospital of Kangda College, Nanjing Medical University, Lianyungang, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Case presentation: A 50-year-old immunocompetent female presented with recurrent low-grade fever and oral mucosal ulceration. Pathogen detection was performed using plasma-based metagenomic next-generation sequencing (mNGS), which identified Conclusions: This case underscores the diagnostic value of mNGS in detecting low-biomass anaerobic infections and proposes a synergistic "mucosal barrier disruption-pathogen translocation" model. It also highlights the potential role of host-directed adjunctive therapy in managing bloodstream infections not associated with prosthetic material.

Indexed as

Bloodstream infectionMetagenomic next-generation sequencingMucosal barrier dysfunctionStaphylococcus saccharolyticusVitamin D deficiency

Identifiers

PMID41216181
PMCPMC12597072

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.