Evidence map›Paper›PMID 41216108›Full record

ArticleCureus2025

Parathyroid Carcinoma in a Patient With End-Stage Renal Disease Initially Suspected With Refractory Secondary Hyperparathyroidism.

Tomohiro Tsuboya, Takeo Ozawa, Tomoaki Asamori, Shotaro Naito, Soichiro Iimori

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Occult Parathyroid Lesions onBiomedicines · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tomohiro TsuboyaNephrology, Institute of Science Tokyo, Tokyo, JPN.
Takeo OzawaNephrology, Institute of Science Tokyo, Tokyo, JPN.
Tomoaki AsamoriHead and Neck Surgery, Institute of Science Tokyo, Tokyo, JPN.
Shotaro NaitoNephrology, Institute of Science Tokyo, Tokyo, JPN.
Soichiro IimoriNephrology, Institute of Science Tokyo, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 50-year-old woman, who developed end-stage renal failure due to immunoglobulin A (IgA) nephropathy, had been on hemodialysis for seven years. One year ago, she underwent evaluation at another hospital for elevated parathyroid hormone (PTH) levels; however, no definitive diagnosis was made, and she was placed under observation. Because secondary hyperparathyroidism (SHPT) was considered the most likely cause in a dialysis patient, her medications were adjusted, but her PTH levels did not improve, and she was referred to our department. Further evaluation revealed a suspicion of parathyroid carcinoma, and parathyroidectomy was performed. Histopathological examination confirmed the diagnosis of parathyroid carcinoma. Postoperatively, her PTH levels normalized promptly. Although secondary hyperparathyroidism is a common cause of hyperparathyroidism in maintenance dialysis patients, this case suggests the importance of considering parathyroid carcinoma as a possible underlying cause.

Indexed as

dialysishemodialysishypercalcemiaparathyroid carcinomaparathyroid hormonesecondary hyperparathyroidism

Identifiers

PMID41216108
PMCPMC12596748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.