Evidence map›Paper›PMID 41216101›Full record

ArticleCureus2025

Baricitinib in the Management of Severe Alopecia Areata: A Report of Two Cases With Sustained Clinical Response.

Zemmez Youssef, Mohamed-Amine Ennaciri, Rachid Frikh, Naoufal Hjira

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zemmez YoussefDermatology Department, Mohamed V Military Hospital, Rabat, MAR.
Mohamed-Amine EnnaciriDermatology Department, Mohamed V Military Hospital, Rabat, MAR.
Rachid FrikhDermatology Department, Mohamed V Military Hospital, Rabat, MAR.
Naoufal HjiraDermatology Department, Mohamed V Military Hospital, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baricitinib has recently received approval from the US Food and Drug Administration (FDA) as a promising treatment option for adults with severe alopecia areata. Beyond this indication, it has demonstrated efficacy in other conditions such as COVID-19 and rheumatoid arthritis. The drug also presents advantages related to cost, minimal invasiveness, and the absence of postoperative management. Nevertheless, its prescription requires careful consideration of potential safety and clinical implications before widespread use. We describe two patients with severe alopecia areata (baseline Severity of Alopecia Tool (SALT) score = 100), who were treated with baricitinib as an alternative to conventional therapies, both of whom showed favorable outcomes with a progressive reduction in SALT score leading to complete regrowth during a 12-month follow-up period.

Indexed as

alopecia areatabaricitinibhair regrowthjanus kinase inhibitorssalt score

Identifiers

PMID41216101
PMCPMC12596848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.