Evidence map›Paper›PMID 41216084›Full record

ArticleCureus2025

Hypoxic Brain Injury Mimicking a Spinal Cord Disease: An Unusual Neurological Consequence of Cardiac Arrest.

Islam Gumaa, Muaiad Mohamed, Maged Kadies

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Islam GumaaRehabilitation Medicine, Devonshire Centre for Neurorehabilitation, Stockport, GBR.
Muaiad MohamedGeneral Surgery, Gadarif Hospital, Gadarif, SDN.
Maged KadiesRehabilitation Medicine, Devonshire Centre for Neurorehabilitation, Stockport, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrest remains a major cause of both death and long-term disability, particularly neurological impairment. The well-known complication of cardiac arrest is hypoxic-ischemic encephalopathy (HIE), typically manifesting with altered consciousness and cognitive impairment. We report the rare case of a 51-year-old man who developed bilateral lower limb weakness and neurogenic bladder after an out-of-hospital cardiac arrest due to an inferior ST-segment elevation myocardial infarction (STEMI). Given the clinical presentation, a spinal cord lesion, such as a watershed ischemic spinal cord stroke, was suspected. However, extensive spinal imaging revealed no abnormalities. Instead, brain MRI findings were consistent with HIE, suggesting cerebral hypoxia as the underlying cause of the patient's lower limb dysfunction. This case highlights the importance of considering HIE as a differential diagnosis in post-cardiac arrest patients presenting with lower limb weakness, particularly when spinal imaging is unremarkable. Early recognition is essential for appropriate management and prognosis.

Indexed as

basal gangliabilateral lower limbcardiac arresthypoxic-ischemic encephalopathywatershed ischemic spinal cord stroke

Identifiers

PMID41216084
PMCPMC12597114

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.