Evidence map›Paper›PMID 41216083›Full record

ArticleCureus2025

Use of Endo GIA™ With Tri-staple™ and Local Muscle Flaps in Neopharyngeal Reconstruction Following Salvage Total Laryngectomy.

Ömer Bayır, Musa Alper Batı, Serhat Tokgöz, Güleser Saylam, Mehmet H Korkmaz

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ömer BayırOtolaryngology - Head and Neck Surgery, Ankara Etlik City Hospital, Ankara, TUR.
Musa Alper BatıOtolaryngology - Head and Neck Surgery, Ankara Etlik City Hospital, Ankara, TUR.
Serhat TokgözGeneral Surgery, Ankara Etlik City Hospital, Ankara, TUR.
Güleser SaylamOtolaryngology - Head and Neck Surgery, Faculty of Medicine, Lokman Hekim University, Ankara, TUR.
Mehmet H KorkmazOtolaryngology - Head and Neck Surgery, Private Clinic, Ankara, TUR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salvage total laryngectomy (STLx) is associated with higher complication rates than primary procedures, particularly in patients with a history of radiation therapy, where delayed wound healing and pharyngocutaneous fistula remain major challenges. Commonly recommended approaches, such as pedicled or free tissue flaps, may reduce complications but often prolong operative time, enlarge the surgical field, and add morbidity. In this technical report, we describe a neopharyngeal reconstruction technique using Endo GIA™ with Tri-Staple™ Technology (Covidien, North Haven, Connecticut), reinforced with local muscle flaps, as an alternative in STLx. After laryngeal mobilization, the neopharynx was closed with a 60-mm stapler, with an additional cartridge when necessary, and reinforced with submucosal and cricopharyngeal sutures. Bilateral sternocleidomastoid sternal heads and strap muscles were rotated over the staple line to provide vascularized support. This approach offered secure closure, shortened operative time, minimized reconstructive complexity, and avoided donor site morbidity, while the local muscle reinforcement enhanced vascularity and reduced the risk of fistula formation in high-risk irradiated patients. We believe that stapler-assisted neopharyngeal closure combined with local muscle flaps represents a practical and effective strategy for STLx, with the potential to lower complication rates, facilitate recovery, and serve as a valuable alternative to more extensive reconstructive procedures.

Indexed as

laryngeal cancerlaryngectomysalvage therapysurgical flapsurgical stapler

Identifiers

PMID41216083
PMCPMC12597087

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.