ArticleCureus2025
Imaging Findings of Atypical Spindle Cell/Pleomorphic Lipomatous Tumors: A Case Series and Systematic Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- CT and MRI imaging features of atypical spindle cell lipomatous tumor in the retroperitoneum: a case report.Frontiers in oncology · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to examine the CT and MRI features of atypical spindle cell/pleomorphic lipomatous tumors (ASCPLTs) through a case series and systematic review. A literature search was conducted using MEDLINE and Scopus databases, covering the period from January 1, 2017, to June 9, 2025. The following keywords were used: ("atypical spindle cell lipomatous tumor") OR ("atypical pleomorphic lipomatous tumor") OR ("atypical spindle cell/pleomorphic lipomatous tumor"). The study included five patients from our institution with histopathologically and immunohistochemically confirmed ASCPLTs, along with 18 additional cases identified from 18 published articles. Imaging findings were reviewed retrospectively. A total of 23 patients with ASCPLTs were analyzed (14 male patients and nine female patients; median age, 60 years; age range, 13-87 years). The median lesion size was 115 mm. Fourteen lesions (61%) were superficial, and nine (39%) were deep. Tumor margins appeared well-defined in 20 (87%) cases and ill-defined in three (13%) cases. A capsule was identified on T2-weighted images in 9/12 (75%) cases. Fatty and non-fatty components were observed in 14/18 (78%) and 15/18 (83%) cases, respectively, with non-fatty components predominating in 13/18 (72%) cases. Imaging patterns were classified as follows: atypical lipomatous tumors in 3/17 (18%) cases, spindle cell lipoma in 3/17 (18%), myxoid liposarcoma in 5/17 (30%), dedifferentiated liposarcoma in 4/17 (22%), and undifferentiated pleomorphic sarcoma in 2/17 (12%). Key imaging characteristics of ASCPLTs included large size (>100 mm), superficial location, well-defined margins, presence of a capsule, and predominance of non-fatty components. While ASCPLTs frequently contained fat, their imaging presentations varied widely.
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