ArticleJPRAS open2025
The role of bovine pericardium matrix in immediate prepectoral breast reconstruction: Insights from the largest published retrospective series.
Article in JPRAS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immediate prepectoral breast reconstruction (IPBR) with biological matrices is a widely adopted technique, traditionally guided by ABS-BAPRAS eligibility criteria. In Europe, their use has declined in recent years, while polyurethane-covered implants have emerged as an alternative in some centers. This study reports the outcomes of IPBR with Exaflex, a biological matrix, performed at CHUVI in a real-world clinical setting.A retrospective analysis was conducted on a cohort of 80 patients and 112 mastectomies from a prospectively maintained database. The mean patient age was 51 years, and the average BMI was 24.3 kg/m2; 21.25 % had a BMI <21 and 18.75 % were smokers. Preoperative MRI showed a pinch test >15 mm in 68.75 % of breasts. Preoperative radiotherapy was administered in 2.67 % of breasts, and 32.1 % received postoperative radiotherapy. 43.75 % of patients presented with two or more concurrent risk factors Nipple-sparing mastectomy (NSM) was the most common technique (92.9 %), and all reconstructions were prepectoral. Mean breast weight was 212.8 g and implant volume 327 cc. Axillary surgery was performed in 59 % of cases (SLNB 55.4 %, ALND 5.3 %).Complication rates included seroma (5.4 %), hematoma (8 %), wound infection (6.25 %), prosthetic infection (4.46 %), skin necrosis (7.14 %), rippling (9.8 %), and capsular contracture (2.67 %). No animation deformities were observed. Aesthetic reoperation occurred in 10.7 % of cases, and reconstruction failure in 1.78 %. Mean follow-up was 13.5 months (median 13). A statistically significant association was observed between postoperative radiotherapy and capsular contracture ( Conclusion: IPBR with Exaflex is a safe and reproducible technique with favorable outcomes. The ABS-BAPRAS criteria are highly selective. However, despite the limitations of our study, our findings suggest that, in experienced hands, these criteria might be cautiously expanded to include NSM patients with selected risk factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.