Evidence map›Paper›PMID 41215821›Full record

ArticleJPRAS open2025

Immobility-induced hypercalcemia following complex lower limb trauma: A case report.

Mai Nishijo, Calver Pang, Keith Anderson, Charles Yuen Yung Loh

Abstract readCase Reports
In one paragraph

Article in JPRAS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mai NishijoDepartment of Plastic Surgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Calver PangDepartment of Plastic Surgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Keith AndersonDepartment of Plastic Surgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Charles Yuen Yung LohDepartment of Plastic Surgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immobilization-induced hypercalcemia is a rare but potentially life-threatening complication in patients with prolonged immobility, particularly in those with severe trauma. We describe a 22-year-old male polytrauma patient with a Gustilo-Anderson grade 3b open tibial-fibular fracture and traumatic brain injury. During prolonged recovery complicated by multiple surgical interventions, he developed moderate hypercalcemia two months post-injury. Common causes such as malignancy and primary hyperparathyroidism were excluded. Hypercalcemia was attributed to prolonged immobilization and successfully managed with intravenous fluids. This case highlights the need for routine calcium monitoring in trauma patients with prolonged immobilization. Early recognition and management of hypercalcemia are critical to prevent serious complications.

Indexed as

Calcium monitoringHypercalcemiaImmobilizationLower limb fracturePolytraumaTrauma rehabilitation

Identifiers

PMID41215821
PMCPMC12596600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.