Evidence map›Paper›PMID 41215806›Full record

Observational studyPeerJ2025

Retrospective study on the association between paternal occupational exposure to agrochemicals and childhood leukemia in Michoacán de Ocampo, México.

Paola Jiménez-Alcántar, Anel Gómez-García, Joel E López-Meza, Alejandra Ochoa-Zarzosa, Luis Andrés Espino-Barajas, Luis Miguel Morales-Manilla, Eloy Pérez-Rivera, Luz Yadira Zúñiga-Quijano, Sergio Gutiérrez-Castellanos

Abstract readObservational Study
In one paragraph

Observational study in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paola Jiménez-Alcántar *Centro Multidisciplinario de Estudios en Biotecnología-FMVZ, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, México.
Anel Gómez-GarcíaCentro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social, Morelia, Michoacán, México.
Joel E López-MezaCentro Multidisciplinario de Estudios en Biotecnología-FMVZ, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, México.
Alejandra Ochoa-ZarzosaCentro Multidisciplinario de Estudios en Biotecnología-FMVZ, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, México.
Luis Andrés Espino-BarajasCentro de Investigaciones en Geografía Ambiental, Universidad Nacional Autónoma de México Campus Morelia, Morelia, Michoacán, México.
Luis Miguel Morales-ManillaCentro de Investigaciones en Geografía Ambiental, Universidad Nacional Autónoma de México Campus Morelia, Morelia, Michoacán, México.
Eloy Pérez-RiveraHospital Infantil "Eva Sámano de López Mateos", Secretaría de Salud de Michoacán, Morelia, Michoacán, México.
Luz Yadira Zúñiga-QuijanoHospital Infantil "Eva Sámano de López Mateos", Secretaría de Salud de Michoacán, Morelia, Michoacán, México.
Sergio Gutiérrez-Castellanos *Centro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social, Morelia, Michoacán, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The constant use of agrochemicals in avocado plantations, because of their susceptibility to pests and diseases, continuously exposes those who work or reside near these orchards to health risks. The purpose of this study was to investigate the association between childhood leukemia cases in Michoacán, paternal occupational exposure to agrochemicals, and environmental exposure due to residential proximity. Methods: A retrospective observational cohort study was performed. We analyzed 430 cases of leukemia in children under 18 years of age diagnosed between 2010-2023. Logistic regression models were used to estimate odds ratios and 95% confidence intervals, adjusted for sociodemographic factors. Survival was analyzed using Kaplan-Meier curves. Results: A total of 46.6% of the parents of children with leukemia in this study had jobs related to the use of agrochemicals ( Conclusions: The epidemiologic evidence found in this study supports the association between paternal occupational exposure to agrochemicals and childhood leukemia. Furthermore, children with leukemia who live in avocado-growing regions have a higher survival rate.

Indexed as

AgrochemicalsLeukemiaOccupational ExposurePaternal ExposureAdolescentChildChild, PreschoolFemaleHumansInfantMaleMexicoPerseaRetrospective StudiesAgrochemicalsAgrochemicalsFarmerLeukemiaPersea

Identifiers

PMID41215806
PMCPMC12596878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.