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ArticleClinical kidney journal2025

Home-based exercise and physical activity intervention after kidney transplantation: impact of exercise intensity (PHOENIX-Kidney). Protocol for a multicentre randomized controlled trial.

Stefan De Smet, Marieke Vandecruys, Jasmine De Beir, Sofie Leunis, Karsten Vanden Wyngaert, Marie Renier, Henriette de Loor, Kaatje Goetschalckx, Maarten Naesens, Delphine De Smedt and 15 more

Registry-linked trialAbstract read
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In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06260579 (A Home-based Exercise and Physical Activity Intervention After Kidney Transplantation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06260579 narecruitingnot on this map

A Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity - a Multicenter Randomized Controlled Trial

TypeinterventionalSponsorKU LeuvenRan2022 to 2029Enrolled147ConditionsPhysical Activity, Exercise Training, Kidney Transplantation, Physical FitnessArmsExercise/physical activity
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Stefan De SmetDepartment of Movement Sciences, Exercise Physiology Research Group, KU Leuven, Leuven, Belgium.
Marieke VandecruysDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.
Jasmine De BeirDepartment of Rehabilitation sciences, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0003-0995-6116
Sofie LeunisDepartment of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.
Karsten Vanden WyngaertDepartment of Internal Medicine and Paediatrics, Nephrology Section, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0001-6063-9971
Marie RenierDepartment of Rehabilitation Sciences, Research Group for Rehabilitation in Internal Disorders, KU Leuven, Leuven, Belgium.
Henriette de LoorDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.
Kaatje GoetschalckxDepartment of Cardiovascular Disease, University Hospitals Leuven, Leuven, Belgium.
Maarten NaesensDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.
Delphine De SmedtDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0001-7035-8508
Francis VerbekeDepartment of Internal Medicine and Paediatrics, Nephrology Section, Ghent University Hospital, Ghent, Belgium.
Ingeborg StalmansDepartment of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.
Steffen FieuwsBiostatistical Centre, KU Leuven, Leuven, Belgium.
Griet GlorieuxDepartment of Internal Medicine and Paediatrics, Nephrology Section, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0002-7641-4707
Jan Van EijgenDepartment of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.
Hanne Van CriekingeDepartment of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.
Jeroen RaesDepartment of Microbiology and Immunology, Rega Institute for Medical Research, Leuven, Belgium.
Sabina De GeestInstitute of Nursing Science, Department Public Health, Faculty of Medicine, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0001-6596-7237
Wim Van BiesenDepartment of Internal Medicine and Paediatrics, Nephrology Section, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0002-4782-5224
Dirk KuypersDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.
Evi NaglerDepartment of Internal Medicine and Paediatrics, Nephrology Section, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0002-8954-6397
Patrick CaldersDepartment of Rehabilitation sciences, Ghent University, Ghent, Belgium.
Diethard MonbaliuDepartment of Microbiology, Immunology and Transplantation, Abdominal Transplantation, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-0506-1609
Véronique CornelissenDepartment of Rehabilitation Sciences, Research Group for Rehabilitation in Internal Disorders, KU Leuven, Leuven, Belgium.
Amaryllis H Van CraenenbroeckDepartment of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-4728-9406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular (CV) disease represents a leading cause of death in kidney transplant recipients (KTRs). Poor physical fitness adds to the increased CV risk of KTRs. Exercise-based rehabilitation and physical activity interventions may prove pivotal in both short and long-term outcomes after kidney transplantation. Methods: PHOENIX-Kidney is a prospective, multicentre, randomized, controlled, single-blinded trial with parallel groups. A total of 147 adult Conclusion: PHOENIX-Kidney is the first adequately powered RCT to address the question of optimal training intensity in KTRs. Moreover, the implementation potential of a home-based exercise programme followed by a physical activity intervention will be formally assessed in a real-world clinical setting. Clinical Trial Registration: Clinicaltrials.gov identifier number: NCT06260579.

Indexed as

cardiovascularexercisekidney transplantationphysical activityquality of life

Identifiers

PMID41215780
PMCPMC12596492

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.