Evidence map›Paper›PMID 41214889›Full record

ArticlePhysiological reports2025

Astrocyte properties in cetacean cortices.

Anu Venkatesh, Abby M McClain, Carolina R Le-Bert, Whitney B Musser, Sam H Ridgway

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Astrocyte properties in cetacean cortices.Physiological reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anu VenkateshNaval Information Warfare Center Pacific, San Diego, California, USA.ORCID 0000-0003-3230-8467
Abby M McClainNaval Information Warfare Center Pacific, San Diego, California, USA.
Carolina R Le-BertNaval Information Warfare Center Pacific, San Diego, California, USA.ORCID 0000-0002-6356-3260
Whitney B MusserNational Marine Mammal Foundation, San Diego, California, USA.
Sam H RidgwayNational Marine Mammal Foundation, San Diego, California, USA.

Funding

Office of Naval Research N0001417WX01558SMART Seed Program
6 · The paper itself

Abstract

Cetacean neurons are far more extensively studied in the scientific literature than the other principal cell type of the central nervous system-glia. To help address this knowledge gap, the current study profiled astrocytes in five cetacean species-Tursiops truncatus (Tt), Orcinus orca (Oo), Ziphius cavirostris (Zc), Pseudorca crassidens (Pc), and Kogia breviceps (Kb) with brain masses ranging from 596 g in Kb to 6215 g for Oo. Using formalin-fixed brain tissues stained with anti-glial fibrillary acidic protein antibodies, astrocyte distributions across cortical regions were profiled for each animal, including measurements of astrocyte diameter. Results showed statistically significant (p < 0.003) effects for cortical layer and species in addition to astrocyte size (cell body) between the animals. The largest astrocytes were found in the larger cetaceans (Pc), although average astrocyte size did not statistically differ from the control (Mus musculus). The results of this investigation advance our knowledge of cetacean astrocyte biology, with translational implications for human conditions such as dementia and traumatic brain injury. Collectively, these findings illustrate a quantitative approach to better understand neuroanatomical variations across cetacean species.

Indexed as

AstrocytesCerebral CortexCetaceaAnimalsFemaleGlial Fibrillary Acidic ProteinMaleGlial Fibrillary Acidic Proteinastrocytescetaceanscortical gliamarine mammal

Identifiers

PMID41214889
PMCPMC12602265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.