Evidence map›Paper›PMID 41214881›Full record

ArticleThe European journal of neuroscience2025

MRI Evaluation of Glymphatic Dysfunction in Cerebral Small Vessel Disease: Hypertensive vs. Normotensive Patients.

Mingming Huang, Xinyue Lyu, Yong Xia, Bo Gao

Abstract read
In one paragraph

Article in The European journal of neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingming HuangDepartment of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.ORCID 0000-0003-3616-7825
Xinyue LyuDepartment of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Yong XiaDepartment of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Bo GaoDepartment of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

2020 Innovation group project of Guizhou Province Educational Commission KY[2021]017Discipline leading talent of the Affiliated Hospital of Guizhou Medical University gyfyxkrc-2023-04Guizhou Province 7th Thousand Innovational and Enterprising Talents GZQ202007086Guizhou Province Science & Technology Innovation Talent Team CXTD[2022]006Guizhou Province Science and Technology Project [2020]4Y159Guizhou Province Science and Technology Project [2021]430National Natural Science Foundation of China 81560281National Natural Science Foundation of China 81871333National Natural Science Foundation of China 82260340National Science Foundation Cultivation Project of the Affiliated Hospital of Guizhou Medical University gyfynsfc[2024]-30
6 · The paper itself

Abstract

The glymphatic system (GS) serves as the brain's waste clearance pathway, with dysfunction implicated in neurodegenerative disorders-particularly cerebral small vessel disease (CSVD). As hypertension is a modifiable risk factor strongly linked to CSVD progression, we compared magnetic resonance imaging-derived (MRI-derived) GS metrics between hypertensive and normotensive CSVD patients. So, in this study, we retrospectively analyzed 72 clinically diagnosed CSVD patients (37 hypertensive [CSVD_HT

Indexed as

Cerebral Small Vessel DiseasesGlymphatic SystemHypertensionAgedBlood PressureFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesWhite MatterALPS indexcerebral small vessel diseaseglymphatic dysfunctionhypertensionperivascular spaces

Identifiers

PMID41214881
PMCPMC12603343

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.