Observational studyBMC cancer2025
The Transdiagnostic Oncology Program (TOP): a multidomain lifestyle intervention to improve the quality of life of cancer survivors - a before-and-after pilot study in primary care.
Observational study in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06809452 (The Transdiagnostic Oncology Program), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Transdiagnostic Oncology Program (TOP): a Combined Lifestyle Intervention to Improve the Quality of Life of Cancer Survivors - a Before-and-after Pilot Study in Primary Care
Who cites it
1 citing paper in PubMed.
- Overall and Cause-Specific Late Mortality in Long-Term Survivors of Early Onset Solid Cancer After Surgery: A Population-Based Retrospective Cohort Study.Annals of surgical oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a need for interdisciplinary primary care-led aftercare programs for the common (transdiagnostic) problems cancer survivors experience to increase their quality of life. The aim of this before-and-after (pre-post) pilot study was to examine the feasibility and preliminary effectiveness of a transdiagnostic, family doctor-led interdisciplinary program to increase quality of life in a heterogeneous group of cancer survivors.
methodsCancer survivors (n = 19) followed a 12-month interdisciplinary aftercare program in the primary care setting, consisting of: family doctor consultation, exercise, mind-body therapy, sleep hygiene, nutrition recommendations, and optional psychological therapy. Eligible cancer survivors who declined participation, were recruited as controls (n = 16). Feasibility and acceptance were assessed through attendance and attrition rates, and an evaluation form. The primary outcome was the change in quality of life from baseline (T0) to post-intervention (T2; 12 months from baseline), as measured with the EORTC QOL-C30, covering global health status, various functional domains, and symptoms. Secondary outcomes included assessments of changes in fatigue (Multidimensional Fatigue Inventory), psychological symptoms (Depression, Anxiety and Stress scale), happiness (Happiness Index), and work ability (Work Ability Index). Intention-to-treat multilevel analyses were conducted.
resultsDropout (n = 3) during the program was related to personal and health issues, and attendance rates and satisfaction scores were satisfactory. At baseline, the intervention group scored significantly worse on several quality-of-life indices, and on secondary outcomes, compared to controls. The intervention group showed significantly larger increases at T2 in physical and social functioning, and decreases in fatigue and anxiety, compared to the control group.
conclusionsThe results suggest that this primary care-led aftercare program is feasible and acceptable. Due to the small sample size and non-randomized design, improvements in quality of life and related outcomes should be interpreted with caution. A randomized controlled trial is warranted.
trial registrationThis study was retrospectively registered at clinicaltrials.gov (NCT06809452).
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