ArticleBMC genomics2025
Integrated physiological, biochemical, and transcriptomic analysis of the cold-sensitive response in Mussaenda anomala.
Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Mussaenda anomala exhibits high sensitivity to low-temperature stress, but its molecular adaptation mechanisms remain poorly understood. In this study, tissue-cultured seedlings were exposed to temperature gradients (25 °C as control, 12 °C, 4 °C, and 0 °C) to investigate cold-stress responses. Physiological analyses revealed increased oxidative damage (increased levels of H₂O₂, relative electrolyte conductivity (REC) and malondialdehyde (MDA)) and chloroplast/mitochondrial impairment, accompanied by downregulation of photosynthetic genes (Psb/Psa/LHCA/LHCB). The plants activated multi-level defenses, including stomatal closure, palisade tissue thickening, starch accumulation, and upregulation of starch/sucrose metabolism genes (SS/Amy). Antioxidant systems (SOD/POD/CAT) were enhanced, alongside hormonal reprogramming (ABA/JA accumulation with auxin suppression). Weighted gene co-expression network analysis (WGCNA) revealed three co-expression modules containing 12 hub genes (BKI1-like, PAO2-like, CDPK1 etc.) potentially regulating cold adaptation. These findings provide the first comprehensive molecular characterization of M. anomala's cold stress response, offering valuable targets for breeding cold-tolerant ornamental plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.