ReviewJournal of cancer survivorship : research and practice2025
Physical activity interventions for women with metastatic breast cancer: a systematic review of published and ongoing randomised controlled trials.
Review in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
purposeWe systematically reviewed published and ongoing physical activity (PA) trials in women with metastatic breast cancer (MBC). We examined (i) the effectiveness of PA interventions and identified (ii) the type of interventions being evaluated, (iii) how they are delivered and (iv) their theoretical basis.
methodsSeven databases and two trial registries were searched in August 2024 for randomised controlled trials, testing any PA intervention in people with MBC, reporting a PA outcome. The Joanna Briggs Institute (JBI) handbook was followed, including quality assessment using the JBI Critical Appraisal Checklist for RCTs. Data were summarised narratively. Intervention details were extracted using the TIDieR framework.
resultsOne thousand six hundred eighty-seven records were screened and 96 assessed for eligibility. Twenty-eight reports were included (13 full reports, 4 protocols, 11 trial registries). Sample sizes ranged from 21 to 357 participants. Twenty-one out of 28 reports were phase II, pilot, or feasibility trials. Most interventions did not cover all types of recommended PA. The methodological quality of studies was moderate. Intervention adherence was moderate to high (≥ 50% in 10 studies). Among studies reporting on safety (9), only one recorded any serious events (two events) related to the intervention. Evidence indicates that PA can improve fatigue, health-related QoL, physical fitness, and functioning over the short and medium term (≤ 6 months).
conclusionsPhysical activity is safe, well adhered to, and improves physical function and QoL in MBC. Future trials could clarify the optimal PA type, duration, delivery mode, and long-term effectiveness. IMPLICATIONS FOR CANCER SURVIVORS: Women with MBC should be supported by healthcare professionals to be active.
Indexed as
Identifiers
41214274What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.