ArticleThe Journal of antibiotics2026
Antibacterial activity and mechanism of optimized THPA conjugated dipeptides against methicillin-resistant Staphylococcus aureus.
Article in The Journal of antibiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
Despite decades of investigation, multidrug-resistant bacterial resistance has become the leading health concern globally related to MRSA infections, where conventional antibiotics have failed in this race. However, the development of short cationic antimicrobial peptides with higher efficacy and low cytotoxicity has encouraged our recent exploration. Herein, we describe the synthesis, characterization, and antibacterial evaluation of tetrahydropiperic acid (THPA) conjugate αβ-hybrid peptides, THPA-Lys-tBu-β
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