Evidence map›Paper›PMID 41214229›Full record

ArticleNPJ digital medicine2025

Automated detection of radiolucent foreign body aspiration on chest CT using deep learning.

Xiaofan Liu, Zhe Chen, Zhiyong Tang, Xun Yang, Yan Jiang, Dan Zheng, Fangfang Jiang, Fang Ni, Shuang Geng, Qiong Qian and 12 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Artificial intelligence in respiratory medicine: From diagnosis to treatment and future directions.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Xiaofan Liu *Department of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Zhe Chen *Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Zhiyong Tang *Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Xun Yang *Department of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Yan JiangDepartment of Radiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Dan ZhengSchool of Medicine, Jianghan University, Wuhan, Hubei 430056, China.
Fangfang JiangDepartment of Biostatistics, University of Iowa, Iowa City, IA 52242, USA.
Fang NiDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Shuang GengDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Qiong QianDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Yan HaoDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Junjie XuDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Yin WangDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Mingyuan ZhuDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Xiaoqing WangDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.
Rob M EwingBiological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton SO17 1BJ, UK. Rob.ewing@soton.ac.uk.
Zehor BelkhatirElectronics and Computer Science, Digital Health & Biomedical Engineering Group, University of Southampton, Southampton SO17 1BJ, UK. z.belkhatir@soton.ac.uk.
Guqin ZhangDepartment of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China. zgqxiaoxiao@126.com.
Hanxiang NieDepartment of Respiratory and Critical Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China. nhxiang@whu.edu.cn.
Yi HuDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China. huyi@zxhospital.com.
Weihua WangDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China. weihuawang2025@163.com.
Yihua WangBiological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton SO17 1BJ, UK. yihua.wang@soton.ac.uk.

Funding

Beijing Medical and Health Public Welfare Foundation YWJKJJHKYJJ-KXCRHX004China Scholarship Council 202308060201China Scholarship Council 202308060211National Key Research and Development Program of China NO.2022YFC2303800National Science foundation of China 62073149National Science foundation of China 82370031Scientific Research Projects from Wuhan Municipal Health Commission WX23A81UK Medical Research Council MR/S025480/1Wuhan Central Hospital's Institutional Discipline Fund 2021XK104
6 · The paper itself

Abstract

Radiolucent foreign body aspiration (FBA) remains diagnostically challenging due to its subtle imaging signatures on chest CT scans, often leading to delayed or missed diagnoses. We present a deep learning model integrating MedpSeg, a high-precision airway segmentation method, with a convolutional classifier to detect radiolucent FBA. The model was trained and validated across three independent cohorts, demonstrating consistent performance with accuracies above 90% and balanced recall-precision metrics. In a blinded independent evaluation cohort, the model outperformed expert radiologists in both recall (71.4% vs. 35.7%) and F1 score (74.1% vs. 52.6%), highlighting its potential to reduce missed cases (false negatives) and support clinical decision-making. This study illustrates the translational potential of artificial intelligence for addressing diagnostically complex and high-risk conditions, offering an effective tool to support radiologists in the assessment of suspected radiolucent foreign body aspiration. Code is available at https://github.com/ZheChen1999/FBA_DL .

Identifiers

PMID41214229
PMCPMC12603148

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.