ArticleNature communications2025
Prognostic value of an abnormal chest X-ray result in predicting the development of tuberculosis.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Risk of progression to pulmonary tuberculosis among household contacts with chest radiographic abnormalities in South Africa.medRxiv : the preprint server for health sciences · 2026Article
- Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data.BMC geriatrics · 2026Article
- Article
- A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2026 Update for Clinicians and Scientists.Pathogens & immunity · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although tuberculosis is preventable, whom to prioritize for preventive interventions is debated. As part of a follow-up to a mass tuberculosis screening, we aimed to evaluate tuberculosis incidence among persons with distinct baseline X-ray results. From March to October 2020, we implemented a mass tuberculosis screening intervention among elderly persons in eastern China. Participants were followed for incident tuberculosis until October 2022. Tuberculosis incidence over two years among participants with differing baseline chest X-ray results were assessed. Physical examinations and X-rays were administered to all participants. Among persons suspected of tuberculosis, computed tomography, culture or GeneXpert MTB/RIF was performed. Among 183,808 participants, 27,796 had a baseline abnormal X-ray. The annualized incidence per 100,000 person-years was 1,525 (95% CI, 989-2,243), 278 (202-373), 325 (218-466), and 61 (50-75) among participants with X-rays suggestive of active, stable, uncertain and normal, respectively. Among persons with X-ray findings suggestive of tuberculosis, the increased hazard was 16.7 (95% CI, 11.9-23.4). These results demonstrate the risk of developing tuberculosis among persons with an abnormal chest X-ray was very high. Combining mass screening with preventive interventions based on X-ray findings should be explored as a combination intervention package to reduce tuberculosis in high-risk populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.