Evidence map›Paper›PMID 41213912›Full record

ArticleNature communications2025

Can five chemically different lamellar crystals self-assemble in a single spherulite?

Eider Matxinandiarena, Ricardo A Pérez-Camargo, Víctor Sebastián, Pengfei Zhang, Viko Ladelta, Nikos Hadjichristidis, Alejandro J Müller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eider MatxinandiarenaPOLYMAT and Department of Polymers and Advanced Materials: Physics, Chemistry and Technology, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, 20018, Donostia-San Sebastián, Spain.
Ricardo A Pérez-CamargoPOLYMAT and Department of Polymers and Advanced Materials: Physics, Chemistry and Technology, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, 20018, Donostia-San Sebastián, Spain.
Víctor SebastiánDepartment of Chemical and Environmental Engineering, Nanoscience Institute of Aragon University of Zaragoza and Aragón Materials Science Institute, ICMA, CSIC, Pedro Cerbuna 12, 50009, Zaragoza, Spain.ORCID http://orcid.org/0000-0002-6873-5244
Pengfei ZhangPolymer Synthesis Laboratory, Chemistry Program, KAUST Catalysis Center, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.ORCID http://orcid.org/0000-0003-4306-7961
Viko LadeltaPolymer Synthesis Laboratory, Chemistry Program, KAUST Catalysis Center, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia.ORCID http://orcid.org/0000-0003-0596-7571
Nikos HadjichristidisPolymer Synthesis Laboratory, Chemistry Program, KAUST Catalysis Center, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955, Saudi Arabia. nikolaos.hadjichristidis@kaust.edu.sa.ORCID http://orcid.org/0000-0003-1442-1714
Alejandro J MüllerPOLYMAT and Department of Polymers and Advanced Materials: Physics, Chemistry and Technology, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, 20018, Donostia-San Sebastián, Spain. alejandrojesus.muller@ehu.es.ORCID http://orcid.org/0000-0001-7009-7715

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semicrystalline polymers with multiple crystallizable blocks provide opportunities to develop materials with hierarchical structures and customized properties, but they also pose unique challenges for understanding their crystallization. In this work, we investigate the crystallization from a miscible melt of a pentablock quintopolymer composed of five potentially crystallizable and biocompatible blocks, composed of polyethylene (PE), poly(ethylene oxide) (PEO), poly(ε-caprolactone) (PCL), poly(L-lactide) (PLLA), and polyglycolide (PGA), with a composition optimized to allow the crystallization of all blocks. Using Differential Scanning Calorimetry, synchrotron Fourier Transform Infrared Spectroscopy, synchrotron in situ Wide-angle and Small-angle X-Ray Scattering, Transmission Electron Microscopy, and Polarized Light Optical Microscopy, we demonstrate that upon cooling from the melt, all covalently linked blocks crystallize in a well-defined sequence: PGA > PLLA > PE > PCL > PEO. During crystallization, well-developed pentacrystalline positive spherulites are produced. This unprecedented level of self-assembly reveals the potential of complex block polymers to design multifunctional crystalline materials.

Identifiers

PMID41213912
PMCPMC12603169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.