Evidence map›Paper›PMID 41213872›Full record

ArticleGut and liver2026

Establishing Epidemiological Cutoff Values for

Jin Hee Noh, Jung Mogg Kim, Hwoon-Yong Jung, Ji Yong Ahn, Sun Mi Lee, Seong Woo Jeon, Yong Hwan Kwon, Jeong Hoon Lee, Kee Don Choi, Eun Jeong Gong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut and liver, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jin Hee NohDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.ORCID 0000-0001-6720-9528
Jung Mogg KimDepartment of Microbiology, Hanyang University College of Medicine, Seoul, Korea.ORCID 0000-0002-6506-7519
Hwoon-Yong JungDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0003-1281-5859
Ji Yong AhnDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-0030-3744
Sun Mi LeeAsan Institute for Life Sciences, Asan Medical Center, Seoul, Korea.ORCID 0000-0003-0716-1192
Seong Woo JeonDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-9539-9389
Yong Hwan KwonDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-0520-9685
Jeong Hoon LeeDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-0778-7585
Kee Don ChoiDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0002-2517-4109
Eun Jeong GongDepartment of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.ORCID 0000-0003-3996-3472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: The absence of standardized clinical minimum inhibitory concentration (MIC) breakpoints for Methods: The MIC distributions for antibiotics commonly used against Results: The tentative ECOFFs for amoxicillin and clarithromycin were 0.125 μg/mL. The ECOFFs for levofloxacin, metronidazole, and tetracycline were 0.5, 8.0, and 0.25 μg/mL, respectively. The ECOFF for rifabutin could not be determined due to insufficient data. On the basis of these ECOFFs, the resistance rate was 17.9% for amoxicillin, 31.9% for clarithromycin, 40.9% for levofloxacin, 24.7% for metronidazole, and 11.5% for tetracycline. Conclusions: This comprehensive analysis defined regional antibiotic resistance patterns and established Korea-specific ECOFFs, providing a foundation for determining clinical breakpoints and optimizing

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialHelicobacter InfectionsHelicobacter pyloriAmoxicillinClarithromycinHumansLevofloxacinMetronidazoleMicrobial Sensitivity TestsRepublic of KoreaTetracyclineAmoxicillinAnti-Bacterial AgentsClarithromycinLevofloxacinMetronidazoleTetracyclineCulture mediaDrug resistanceMicrobial sensitivity testsReference values

Identifiers

PMID41213872
PMCPMC12800676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.