Evidence map›Paper›PMID 41212826›Full record

ArticleEuropean heart journal. Cardiovascular Imaging2026

A double-blind, randomized placebo-controlled trial examining the effect of MitoQ on myocardial energetics in patients with dilated cardiomyopathy.

Brian P Halliday, Ruth Owen, Aaraby Ragavan, Katherine L Smith, Ben Statton, Alaine Berry, Alex Kasiakogias, Zoi Tsoumani, Mayooran Shanmuganathan, Jason N Dungu and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal. Cardiovascular Imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Brian P HallidayNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.ORCID 0000-0002-5876-1748
Ruth OwenDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Aaraby RagavanNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
Katherine L SmithNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
Ben StattonMedical Research Council Laboratory of Medical Sciences, Imperial College London, London, UK.
Alaine BerryMedical Research Council Laboratory of Medical Sciences, Imperial College London, London, UK.
Alex KasiakogiasRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.
Zoi TsoumaniRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.
Mayooran ShanmuganathanRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.
Jason N DunguDepartment of Cardiology, Basildon and Thurrock Hospitals NHS Foundation Trust, Basildon, Essex, UK.
Antonio de MarvaoDepartment of Cardiology, Guy's and St Thomas'' NHS Foundation Trust, London, UK.
Upasana TayalNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
James S WareNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
Declan P O'ReganMedical Research Council Laboratory of Medical Sciences, Imperial College London, London, UK.
Dudley J PennellNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
John G F ClelandSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.ORCID 0000-0002-1471-7016
Sanjay K PrasadNational Heart and Lung Institute, Imperial College London, Sydney Street, London SW3 6NP, UK.
John GregsonDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-6084-166X
Michael P MurphyMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
Oliver J RiderOxford Centre for Clinical MR Research (OCMR), Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-1295-7769
Ladislav ValkovičOxford Centre for Clinical MR Research (OCMR), Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Funding

Agentura na Podporu Vyskumu a Vyvoja 21-0299Antipodean PharmaceuticalsAPVVBPHBritish Heart Foundation CH/P/23/80008British Heart Foundation RE/24/130023British Heart Foundation RG/19/6/34387British Heart Foundation Intermediate Clinical Research Fellowship FS/ICRF/21/26019Medical Research Council MC_UP_1605/13NIHR Imperial Biomedical Research CentreRosetrees TrustRoyal Society 221805/Z/20/ZSir Henry Dale FellowshipSlovak Grant Agencies VEGA 2/0004/23Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dilated cardiomyopathyheart failuremitochondrial dysfunctionoxidative stress

Identifiers

PMID41212826
PMCPMC12857217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.