ArticleAmerican journal of physiology. Cell physiology2025
Hemizygous mutation of
James G Tidball, Lina Petrossian, Cynthia M McKee, Michelle Wehling-Henricks
Abstract read
In one paragraphArticle in American journal of physiology. Cell physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
4 authors.
James G TidballMolecular, Cellular & Integrative Physiology Program, University of California, Los Angeles, California, United States.ORCID 0000-0003-1202-8038 Lina PetrossianDepartment of Integrative Biology and Physiology, University of California, Los Angeles, California, United States.ORCID 0009-0001-7084-7296 Cynthia M McKeeMolecular, Cellular & Integrative Physiology Program, University of California, Los Angeles, California, United States.
Michelle Wehling-HenricksDepartment of Integrative Biology and Physiology, University of California, Los Angeles, California, United States.
Funding
Training in Molecular, Cellular &Integrative PhysiologyT32GM065823 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIDBALL, JAMES G · 2003 to 2017
$2.1MMyeloid-cell mediated mechanisms driving muscle growth and regenerationR01AR066036 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIDBALL, JAMES G · 2014 to 2018
$1.8MImmune cell regulation of the regeneration of dystrophic muscleR01AR062579 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIDBALL, JAMES G · 2014 to 2018
$1.7MNovel mechanisms regulating muscle growth and regeneration: elucidating the Klotho/Jmjd3/Wnt axisR01AR075768 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIDBALL, JAMES G · 2020 to 2024
$1.7MKlotho and epigenetic regulation of muscle stem cellsF31AR071782 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCKEE, CYNTHIA · 2018 to 2020
$110kHHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) F31AR071782HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) RO1AR062579HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) RO1AR066036HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) RO1AR075768HHS | NIH | National Institute of General Medical Sciences (NIGMS) T32GM065823NIAMS NIH HHS F31 AR071782NIAMS NIH HHS R01 AR062579NIAMS NIH HHS R01 AR066036NIAMS NIH HHS R01 AR075768NIGMS NIH HHS T32 GM065823
6 · The paper itselfAbstract
Development of myogenic cells, called satellite cells, is determined by transcription factors that regulate their quiescence (e.g., Pax7), activation (e.g., MyoD), and terminal differentiation (e.g., myogenin). Demethylation of lysine 3 on histone 27 (H3K27) activates expression of
Indexed as
HistonesJumonji Domain-Containing Histone DemethylasesMuscle DevelopmentMutationPAX7 Transcription FactorSatellite Cells, Skeletal MuscleAnimalsCell DifferentiationMethylationMiceMyoD ProteinMyogeninPromoter Regions, GeneticHistonesJumonji Domain-Containing Histone DemethylasesKdm6b protein, mouseMyoD1 myogenic differentiation proteinMyoD ProteinMyogeninPax7 protein, mousePAX7 Transcription Factormuscle developmentmyogenesisskeletal muscle
Identifiers
PMID41212538
PMCPMC12707994
What OpenQuestion holds
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